Table 1.
Plasma IL‐38 correlates inversely with systemic mediators of inflammation in overweight subjects
| Plasma IL‐38 correlation with | Spearman r (95% CI) | p value |
|---|---|---|
| hsCRP | −0.16 (−0.27 to –0.04) | 0.008 |
| Leptin | −0.13 (−0.25 to –0.01) | 0.024 |
| IL‐6 | −0.12 (−0.23 to 0.001) | 0.045 |
| IL‐1Ra | −0.12 (−0.23 to 0.003) | 0.049 |
| IL‐1β | −0.10 (−0.22 to 0.01) | 0.076 |
| VEGF | −0.06 (−0.17 to 0.06) | 0.338 |
| Adiponectin | −0.048 (−0.17 to 0.07) | 0.414 |
| IL‐18Bp | −0.04 (−0.16 to 0.07) | 0.444 |
| IL‐18 | −0.04 (−0.16 to 0.08) | 0.500 |
| Resistin | −0.03 (−0.15to 0.09) | 0.579 |
| Alpha‐1 antitrypsin | 0.01 (−0.11 to 0.13) | 0.848 |
Plasma IL‐38 correlates with circulating markers of inflammation in a cohort of 296 overweight individuals at risk for cardiovascular disease. Each cytokine was measured during a single ELISA using aliquotted samples. Shown are the Spearman correlations including the 95% confidence interval and the respective p value.