TABLE 2.

Microarray analysis of genes related to NASH and NASH‐associated HCC: Eleven genes related to NASH were differentially expressed between the T09 + CCl₄ and CCl₄ groups

Relation	Gene symbol	Gene name (description)	Fold change	P‐value	Regulation
Oxidative stress	Cd14	CD14 antigen	2.525	0.042	Upregulation
	Dnmt3b	DNA methyltransferase 3B	2.043	0.014	Upregulation
	Gstm2	Glutathione S‐transferase Mu 2	2.101	0.044	Upregulation
	Pil3cd	Phosphatidylinositol 3‐kinase catalytic delta polypeptide	2.088	0.011	Upregulation
Hepatic steatosis	Acot1	Acyl‐CoA thioesterase 1	2.124	0.014	Upregulation
	Lpl	Lipoprotein lipase	6.301	0.005	Upregulation
	Trib3	Tribbles homolog 3 (Drosophila)	0.395	0.044	Downregulation
Hepatic fibrosis	Lepr	Leptin receptor	6.455	0.038	Upregulation
	Lgals3	Lectin, galactose binding, soluble 3	2.049	0.038	Upregulation
Inflammation	Tfrc	Transferrin receptor	2.725	0.005	Upregulation
	Fcgr4	Fc receptor, IgG, low affinity IV	2.379	0.004	Upregulation

Liver samples from two to four mice in the T09 + CCl₄ and CCl₄ groups were used for the microarray analysis.

HCC, hepatocellular carcinoma; NASH, non‐alcoholic steatohepatitis.