TABLE 3.

Microarray analysis of genes related to NASH and NASH‐associated HCC: Eight genes related to HCC and NASH were differentially expressed between tumor tissue and adjacent nontumor tissue in the T09 + CCl₄ group

Relation	Gene symbol	Gene name (description)	Fold change	P‐value	Regulation
Hepatocellular carcinoma	Cfp	Complement factor properdin	2.688	0.009	Upregulation
	Cd5l	CD5 antigen‐like	2.371	0.003	Upregulation
	Vsig4	V‐set and immunoglobulin domain containing 4	2.346	0.014	Upregulation
	Sirt3	Sirtuin 3	0.487	0.036	Downregulation
NAFLD	Lpl	Lipoprotein lipase	5.12	0.009	Upregulation
	Ucp2	Uncoupling protein 2	2.121	0.042	Upregulation
Apoptosis ↓	Src	Rous sarcoma oncogene	3.755	0.025	Upregulation
	Fgr	Gardner–Rasheed feline sarcoma viral (Fgr) oncogene homolog	3.142	0.004	Upregulation

Liver samples from two to four mice in the T09 + CCl₄ and CCl₄ groups were used for the microarray analysis.

HCC, hepatocellular carcinoma; NASH, non‐alcoholic steatohepatitis.