TABLE 4.
Microarray analysis of genes related to NASH and NASH‐associated HCC: Four genes related to HCC and NASH were differentially expressed in tumor tissue between the T09 + CCl4 and CCl4 groups
Relation | Gene symbol | Gene name (description) | Fold change | P‐value | Regulation |
---|---|---|---|---|---|
Hepatocellular carcinoma | Fam83e | Family with sequence similarity 83, member E | 9.419 | 0.004 | Upregulation |
Src | Rous sarcoma oncogene | 3.755 | 0.003 | Upregulation | |
NAFLD | Lpl | Lipoprotein lipase | 3.790 | 0.048 | Upregulation |
Hepatic fibrosis | Lepr | Leptin receptor | 2.455 | 0.033 | Upregulation |
Liver samples from two to four mice in the T09 + CCl4 and CCl4 groups were used for the microarray analysis.
HCC, hepatocellular carcinoma; NASH, non‐alcoholic steatohepatitis.