Table 7.

Consensus statements: retinoid effects on bone

	SORT
Long‐term use of systemic retinoids in ichthyosis/ DOC is associated with skeletal concerns.	I, A
The toxic effects of systemic retinoid use on bone are strongly dependent on dose and duration.	I, A
Potential bone toxicity should not preclude long‐term systemic retinoid use in patients with ichthyosis if there is a clear clinical benefit.	III, C
Genetic risk and modifiable factors that affect bone health, such as diet and physical activity, may impact susceptibility to systemic retinoid bone toxicity and should be discussed with the patient.	II, C