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. 2020 Nov 7;31(3):529–541. doi: 10.1111/sms.13865

FIGURE 2.

FIGURE 2

A and B) Effects of 4 h low‐intensity cycling with (E&S, panel A) or without sprint intervals (E, panel B) on mRNA abundances of markers of mitochondrial function, angiogenesis, ion transport, and protein turnover in m. vastus lateralis of elite cyclists, measured directly after (Post) and 3 h exercise (3 h). Values are log2‐fold changes with 95% CI. C, Differences in responses between E&S and E. Markers of mitochondrial function: peroxisome proliferator‐activated receptor gamma coactivator‐1α splice 1 (PGC‐1αs1), pyruvate dehydrogenase kinase 4 (PDK4), mitochondrial transcription factor A (TFAM), angiogenesis: vascular endothelial growth factor A (VEGFA) and thrombospondin (THBS1). Markers of ion transport: Na+‐K+ α1 (ATP1A1), Na+‐K+ α2 (ATP1A2), and Na+‐K+ β1 (ATP1B1), chloride voltage‐gated channel 1 (CLC‐1), sodium‐hydrogen exchanger 1 (SLC9A1/NHE1). Markers of protein synthesis regulation: insulin‐like growth factor 1 (IGF1), myostatin, muscle ring finger 1 (MuRF1), peroxisome proliferator‐activated receptor gamma coactivator‐1α splice 4 (PGC‐1αs4). * indicates significant (P < .05) difference from pre‐exercise, § indicates significant (P < .05) difference in response between conditions, tendencies to difference in responses are indicated by P‐values. n = 12