Table 3.
Univariate and multivariable analysis of all‐cause in‐hospital mortality
| Variables |
All (n = 278) |
Survival (n = 186) |
% |
Death (n = 92) |
% |
Univariate P‐value |
Multivariate OR (95% CI), P‐value |
|---|---|---|---|---|---|---|---|
| Age | 0.019 | ||||||
| ≤ 35 years | 172 | 124 | 66.67 | 48 | 52.17 | Ref. | |
| > 35 years | 106 | 62 | 33.33 | 44 | 47.83 | 2.324 (0.978–5.652), 0.090 | |
| CD4 count | 0.001 | ||||||
| ≤ 30 cells/µL | 140 | 81 | 43.55 | 59 | 64.13 | Ref. | |
| > 30 cells/µL | 138 | 105 | 56.45 | 33 | 35.87 | 0.472 (0.266–0.840), 0.011 | |
| Concurrent pulmonary infections | 0.613 | ||||||
| No | 148 | 101 | 54.30 | 47 | 51.09 | ||
| Yes | 130 | 85 | 45.70 | 45 | 48.91 | ||
| Therapeutic regimens | 0.002 | ||||||
| TMP/SMZ monotherapy (group 1) | 135 | 78 | 41.94 | 57 | 61.96 | Ref. | |
| TMP/SMZ + caspofungin (groups 2, 3 and 4) | 143 | 108 | 58.06 | 35 | 38.04 | 0.402 (0.225–0.715), 0.002 |
OR, odds ratio; CI, confidence interval; TMP/SMZ, trimethoprim/sulfamethoxazole.