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. 2020 Aug 5;288(4):1163–1178. doi: 10.1111/febs.15478

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© 2020 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Simplified reaction pathways for UDP‐apiose/xylose synthase (UAXS), UDP‐xylose synthase (UXS), and UDP‐glucuronic acid 4‐epimerase (UGAepi). The routes leading to decarboxylation are highlighted in red (UAXS) and blue (UXS), and position of CO₂ is assigned with a yellow circle. Orientation of the C4‐hydroxyl group in the products is equatorial in case of UDP‐xylose (UAXS, UXS) and axial in UDP‐GalA (UGAepi). UDP‐GlcA, uridine diphosphate glucuronic acid; UDP‐GalA, uridine diphosphate galacturonic acid.