Figure 12.

A) Synthesis of TCPP(Fe)@MOF‐SA and its electrochemical DNA sensing. B) Differential pulse voltammogram (DPV) responses of TCPP(Fe)@MOF‐SA to different concentrations of the target DNA from 0 to 10 nm. C) DPV responses of FeTCPP@MOF‐SA to 100 pm of different DNA sequences: a) target DNA, b) single‐base‐mismatched DNA, c) two‐base‐mismatched DNA, d) three‐base‐mismatched DNA, and e) random DNA in the catalytic system of o‐PD/H₂O₂. (A–C) Reproduced with permission. ^[86a] Copyright 2015, American Chemical Society. D) Preparation of the hemin‐encapsulated Fe‐MIL‐88 based electrochemical biosensor and the TB detection principle. E) DPV of TB detection at different concentrations from 0 to 30 nm. F) Specificity of the biosensor toward different samples: a) no analyte, b) 100 nm Apo‐A1, c) 100 nm Hb, d) 100 nm l‐Cys, e) 10 nm TB, and f) 100 nm Apo‐A1+100 nm Hb+100 nm l‐cys+10 nm TB. (D–F) Reproduced with permission. ^[26c] Copyright 2015, Royal Society of Chemistry.