. Author manuscript; available in PMC: 2021 Oct 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2020 Jun 26;1867(10):118786. doi: 10.1016/j.bbamcr.2020.118786

Table 1.

Total number of HTS hits compared with total number of compounds screened by kinase target.

Target	# Screened Compounds	# Hits	Hit %
Src	31	20	0.65
JAK	47	28	0.60
PKC	21	12	0.57
VEGFR	64	34	0.53
GSK3	33	17	0.52
NF-kB	36	18	0.50
Raf	24	11	0.46
FLT3	11	5	0.45
STAT3	7	3	0.43
Akt	29	11	0.38
p38 MAPK	27	10	0.37
MEK	28	9	0.32
Raf	23	7	0.30
Wee1	7	2	0.29
Syk	18	5	0.28
PI3K	64	16	0.25
EGFR	75	13	0.17
mTOR	37	6	0.16