Table 1.
First author, year, country | Sample size | Study design | Mood disorder typea | Anxiety disorder typea | Diagnostic criteria | Risk estimate type | Control variables | Quality reporting score |
---|---|---|---|---|---|---|---|---|
Adam, 2012, Germany | 4181 | CS | DEP, DYS, BIPOLAR, MOOD | OCD | DSM‐IV | aOR | Age, sex | 15 |
Alonso, 2004, Multiple countries | 21 425 | CS | DEP, DYS | GAD, PTSD, SO, SP, AGO, PD | DSM‐IV | OR | ‐ | 15 |
Alvarenga, 2016, Brazil | 2512 | CS | DEP, BIPOLAR, MOOD | OCD | DSM‐IV | ORb | ‐ | 12 |
Andrews, 2002, Australia | 10 641 | CS | DEP, DYS | GAD, OCD, PTSD, PD, AGO, SO | DSM‐IV | OR, aOR | Mental disorders | 14 |
Angst, 2005, Switzerland | 591 | PC | DEP, BIPOLAR | OCD | DSM‐IV | aOR | Sex | 12 |
Arillo Crespo, 1998, Spain | 237 | CS | DEP | SP, AGO, SO, PTSD, PD, ANX | DSM‐III‐R | OR | ‐ | 11 |
Autonell, 2007, Spain | 5473 | CS | DYS | GAD, PTSD, AGO, SO, SP | DSM‐IV | aOR | Sociodemographic variables | 14 |
Beekman, 2000, the Netherlands | 3056 | PC | DEP | ANX | DSM‐III | ORb | ‐ | 12 |
Beesdo, 2007, Germanyc | 3021 | PC | MOOD | SO | DSM‐IV | OR | ‐ | 15 |
Biederman, 2005, USA | 1031 | CC | DEP | PD | DSM‐III‐R | ORb | ‐ | 11 |
Blanco, 2017, USA | 36 309 | PC | BIPOLAR | AGO, PTSD | DSM‐5 | aOR | Sex, age, race, marital status, education, household income, urbanicity, region, and mental disorders | 16 |
Boyd, 1984, USA | 11 519 | CS | DEP | PD, AGO, SP, OCD | DSM‐III | OR | ‐ | 11 |
Bromet, 2005, Ukraine | 4725 | CS | DEP, MOOD | GAD, PD, ANX | DSM‐IV | OR | ‐ | 15 |
Bruce, 2001, USA | 1492 | PC | DEP, DYS | PTSD | DSM‐IV | ORb | 10 | |
Cairney, 2007, Canada | 12 792 | CS | DEP | SO | DSM‐IV | aOR | Did not specify | 15 |
Cairney, 2008, Canada | 36 984 | CS | DEP | SO, ANX | DSM‐IV | ORb | ‐ | 11 |
Carter, 2001, Germany | 4181 | CS | DEP, DYS, MOOD | GAD, PD, AGO, SO, SP, ANX | DSM‐IV | aOR | Age, sex | 15 |
Cederlof, 2015, Swedenc | 19 814 | CC | BIPOLAR | OCD | ICD | RR | 13 | |
Chartier, 2003, Canada | 8116 | CS | DEP, DYS, BIPOLAR | SO | DSM‐III‐R | aOR | Age, sex, education | 16 |
Chavira, 2004, USA | 1173 | CS | DEP | SAD, GAD, SP, SO | DSM‐IV | aOR | Sex | 14 |
Chen, 1995, USA | 18 103 | CS | DEP, BIPOLAR | PD | DSM‐III | aOR | Age, sex, race, marital status, education, socioeconomic status, history of alcohol and drug abuse | 14 |
Chen, 2017, China | 512 891 | CS | DEP | GAD | DSM‐IV | aOR | Education, household income, occupation, smoking, alcohol, BMI, physical activity, chronic disease, mental disorders | 16 |
Chou, 2009, USA | 13 420 | PC | BIPOLAR, DYS | SO | DSM‐IV | aOR | Age, sex, race, marital status, education, employment status, personal income, psychosocial risk factor, childhood experience, childlessness, foreign‐born, living alone, number of stressful life events, comorbid disorders | 15 |
Chou, 2009, USA | 34 653 | PC | DYS, BIPOLAR | SP | DSM‐IV | aOR | Demographic variables, psychiatric disorders | 15 |
Chou, 2010, USA | 13 420 | PC | DYS | PD | DSM‐IV | aOR | Age, sex, race, marital status, education, employment status, personal income, psychosocial risk factor, number of stressful life events, comorbid disorders | 15 |
Choy, 2007, USA | 5877 | CS | DEP | SP | DSM‐III‐R | OR, aOR | Age, sex, race, marital status, income, education, mental disorders | 14 |
Chuan, 2008, Singapore | 1092 | CS | DEP | ANX | DSM‐IV | OR, aOR | Age, sex, race, education, housing type, employment status, marital status, living arrangements | 16 |
Copeland, 2013, USA | 2967 | CS, PC | DEP, DYS | GAD, SAD, SO | DSM‐IV | OR, aOR | Mental disorders | 16 |
Corna, 2007, Canada | 12 792 | CS | DEP | PD | DSM‐IV | OR, aOR | Age, sex, marital status, income adequacy, education, language spoken, geographic location of residence, chronic health problems, limitations in ADLs/IADLS, mental disorders | 15 |
Costello, 2003, USAc | 6674 | PC | MOOD | ANX | DSM‐IV | OR, aOR | Mental disorders | 13 |
Coyne, 1994, USA | 1928 | CS | DEP | ANX | DSM‐IV | ORb | ‐ | 10 |
Cyranowski, 2012, USA | 939 | PC | DEP | ANX | DSM‐IV | ORb | ‐ | 12 |
Davidson, 1991, USA | 4423 | PC | DEP | PTSD | DSM‐III | OR | ‐ | 10 |
de Graaf, 2002, the Netherlands | 7076 | PC | DEP, DYS, BIPOLAR | ANX | DSM‐IV | OR | ‐ | 12 |
de Graaf, 2003, the Netherlands | 7076 | PC | DEP, DYS, BIPOLAR | PD, AGO, SP, SO, GAD, OCD | DSM‐IV | OR | ‐ | 13 |
Depla, 2008, the Netherlands | 7076 | PC | DEP, DYS, BIPOLAR | SP | DSM‐III‐R | aOR | Age, sex, other specific fears | 15 |
Douglass, 1995, New Zealand | 1037 | PC | DEP, DYS | OCD | DSM‐III‐R | ORb | ‐ | 11 |
Essau, 1999, Germany | 1035 | CS | DEP | PD | DSM‐IV | ORb | ‐ | 11 |
Essau, 2003, Germany | 1444 | CS | DEP, DYS | ANX | DSM‐IV | OR | ‐ | 13 |
Faravelli, 2004a, Italy | 2500 | CS | DEP, DYS | GAD, OCD, PD, SO, SP | DSM‐IV | ORb | ‐ | 9 |
Faravelli, 2004b, Italy | 2363 | CS | DEP, DYS | GAD, OCD, PD, SO, SP | DSM‐IV | ORb | ‐ | 11 |
Fehm, 2008, Germany | 4181 | CS | DEP, DYS, BIPOLAR, MOOD | SO | DSM‐IV | OR | ‐ | 13 |
Fineberg, 2013, Switzerland | 591 | PC | DEP, BIPOLAR | OCD | DSM‐III | OR | ‐ | 13 |
Fleitlich‐Bilyk, 2004, Brazil | 1251 | CS | DEP | ANX | DSM‐IV | aOR | Mental disorders | 15 |
Ford, 2003, Multiple countries | ‐d | CS | DEP | ANX | DSM‐IV | aOR | Mental disorders | 15 |
Fung, 2017, Hong Kong | 5719 | CS | DEP | ANX | ICD‐10 | ORb | ‐ | 11 |
Gabilondo, 2010, Spain | 5473 | CS | DEP | GAD, AGO, SP, SO, PTSD, PD, ANX | DSM‐IV | aOR | Sex, education, marital status | 15 |
Glaesmer, 2012, Germany | 5033 | CS | DEP | PTSD | DSM‐IV, ICD‐10 | aOR | Age, sex | 15 |
Goncalves, 2011, Australia | 8841 | CS | DEP | GAD | DSM‐IV | OR, aOR | Age, sex, living arrangements, financial problems, frequency family contact, caregiver status, stressful life events, worry about illness, exercise, chronic illness, functional limitations, self‐assessed health, medication, smoking, family history of anxiety | 13 |
Goodwin, 2004, Germanyc | 3021 | PC | DEP, DYS, BIPOLAR, MOOD | PD | DSM‐IV | aOR | Age, sex | 13 |
Grabe, 2001, Germany | 4093 | PC | DEP, DYS, BIPOLAR | OCD | DSM‐IV | OR | ‐ | 14 |
Grant, 2005, USA | 43 093 | PC | BIPOLAR, DYS, MOOD | GAD | DSM‐IV | aOR | Age, race, sex, marital status, education, income, urbanicity, region of country | 15 |
Grant, 2005, USA | 43 093 | PC | DYS, BIPOLAR, MOOD | SO | DSM‐IV | aOR | Age, race, marital status, education, income, urbanicity, region | 15 |
Grant, 2005, USA | 43 093 | PC | BIPOLAR | PD, SO, SP, GAD, ANX | DSM‐IV | OR, aOR | Age, race, marital status, education, income, urbanicity, region | 15 |
Gratzer, 2004, Canada | 8116 | CS | DEP | ANX | DSM‐III‐R | ORb | ‐ | 10 |
Grenier, 2011, Canada | 2798 | CS | DEP | SP | DSM‐IV | aOR | Age, sex, socioeconomic status | 16 |
Gureje, 2010, Nigeria | 6752 | CS | DEP | ANX | DSM‐IV | aOR | Sex, education, marital status | 16 |
Hasin, 2005, USA | 43 093 | PC | DEP | PD, SO, SP, GAD, ANX | DSM‐IV | OR, aOR | Age, sex, race, marital status, education, income, region, urbanicity | 15 |
Hauffa, 2011, Germany | 2510 | CS | DEP | PTSD | DSM‐IV | ORb | ‐ | 11 |
He, 2009, China | 8487 | CS | MOOD | ANX | DSM‐IV | ORb | ‐ | 10 |
Hecht, 1990, Germany | 1366 | PC | MOOD | ANX | DSM‐III | ORb | ‐ | 10 |
Hek, 2011, the Netherlands | 6007 | PC | MOOD | GAD, AGO, ANX | DSM‐IV | aOR | Age, sex, education, living alone, cognitive status | 16 |
Hunt, 2002, Australia | 10 641 | CS | DEP, DYS, MOOD | GAD | DSM‐IV | aOR | Mental disorders | 15 |
Jaffee, 2002, New Zealandc | 1037 | PC | DEP | ANX | DSM | aOR | Sex | 13 |
Jeon, 2007, South Korea | 6275 | CS | DEP, MOOD | PTSD | DSM‐IV | aOR | Age, sex, education | 15 |
Kang, 2016, South Koreac | 1204 | PC | DEP | ANX | AGECAT | OR, aOR | Sex, housing, stressful life event, clinical factor | 15 |
Kashani, 1988, USA | 150 | CS | DEP | ANX | DSM‐III | ORb | ‐ | 10 |
Katona, 1997, UK | 774 | CS | DEP | GAD, PHOBIA | CARE | ORb | ‐ | 8 |
Kawakami, 2004, Japan | 1029 | CS | MOOD | ANX | DSM‐III‐R | ORb | ‐ | 15 |
Kessler, 1995, USA | 8098 | CS | DYS | PTSD | DSM‐III‐R | OR | ‐ | 13 |
Kessler, 1996, USAc | 8098 | CS | DEP | GAD, AGO, SP, SO, PTSD, ANX | DSM‐III‐R | OR | ‐ | 15 |
Kessler, 1997, USA | 8098 | CS | BIPOLAR | GAD, AGO, SP, SO, PD, PTSD, ANX | DSM‐III‐R | OR | ‐ | 13 |
Kessler, 1999, USA | 11 130 | CS | DEP | GAD | DSM‐III‐R | ORb | ‐ | 11 |
Kessler, 1999, USAc | 8098 | CS | BIPOLAR | SO | DSM‐III‐R | aOR | Age, sex, race, person‐year | 14 |
Kessler, 2002a, Multiple countriesc | 20 189 | CS | DEP, DYS, MOOD | GAD | DSM‐III‐R | OR | ‐ | 15 |
Kessler, 2002b, USA | 8098 | CS | DEP | GAD | DSM‐III‐R | ORb | ‐ | 11 |
Kim, 2016, South Korea | 3013 | CS | BIPOLAR | GAD, OCD, AGO, SO, SP, PTSD, PD, ANX | DSM‐IV | OR | ‐ | 14 |
Kolada, 1994, Canada | 3258 | CS | DEP, DYS | OCD | DSM‐III | ORb | ‐ | 11 |
Lampe, 2003, Australia | 10 641 | CS | DEP, DYS | SO | DSM‐IV | aOR | Mental disorders | 14 |
Leray, 2011, France | 36 015 | CS | DEP | GAD, SO, PD, AGO, PTSD, ANX | ICD‐10 | aOR | Socio‐demographics | 15 |
Lewinsohn, 1993, USA | 1710 | PC | BIPOLAR | ANX | DSM‐III‐R | OR | ‐ | 12 |
Lewinsohn, 1995, USA | 1709 | PC | BIPOLAR | SAD, PD, PHOBIA, ANX | DSM‐III‐R | ORb | ‐ | 11 |
Lewinsohn, 1997, USA | 1709 | PC | DEP, DYS, BIPOLAR | PD, SO, SP, OCD, SAD, OVRANX, ANX | DSM‐III‐R | aOR | Sex, mental disorders | 15 |
Lim, 2005, Singapore | 2847 | CS | DEP, DYS | GAD | DSM‐IV | ORb | ‐ | 12 |
Magee, 1996, USA | 8098 | CS | DYS, MOOD | AGO, SP, SO | DSM‐III‐R | OR | ‐ | 15 |
Magklara, 2015, Greece | 5614 | CS | DEP | GAD, OCD, PD, AGO, PHOBIA | ICD‐10 | aOR | Age, sex | 16 |
Martin‐Merino, 2010, Multiple countries | 97 170 | nested CC | DEP | ANX | READ | aOR | Age, sex, calendar year, smoking, primary care physician visits, stress, sleep and ANXs | 12 |
McCabe, 2006, Canada | 12 792 | CS | DEP | AGO | DSM‐IV | OR, aOR | Did not specify | 15 |
McEvoy, 2011, Australia | 8841 | CS | DEP, DYS, BIPOLAR, MOOD | ANX | DSM‐IV | OR | ‐ | 13 |
Mergl, 2007, Germany | 394 | CS | DEP, DYS | ANX | ICD‐10 | OR | 10 | |
Merikangas, 1996, Multiple countries | ‐d | CS, PC | DEP | GAD, PD, AGO, SP, SO, ANX | DSM‐III, DSM‐III‐R | OR | ‐ | 13 |
Merikangas, 2003, Switzerland | 4547 | PC | DEP | ANX | DSM | aOR | Mental disorders, sex, SCL‐90 risk group | 14 |
Merikangas, 2011, Multiple countries | 61 392 | CS | BIPOLAR | GAD, PTSD, OCD, AGO, PD, SP, SO, SAD, ANX | DSM‐IV | aOR | Age, age‐squared, country | 16 |
Mitchell, 2004, Australia | 10 641 | CS | BIPOLAR | GAD, OCD, PTSD, PD, AGO, SO | DSM‐IV | aOR | Mental disorders | 15 |
Moffitt, 2007, New Zealand | 1037 | PC | DEP | GAD | DSM | OR | 13 | |
Mohammadi, 2006, Iran | 25 180 | CS | DEP, BIPOLAR | SO | DSM‐IV | OR | ‐ | 13 |
Mohammadi, 2007, Iran | 25 180 | CS | DEP, BIPOLAR | OCD | DSM‐IV | OR | ‐ | 10 |
Munyandamutsa, 2012, Rwanda | 1000 | CS | DEP | PTSD | DSM‐IV | OR | ‐ | 15 |
Murphy, 2004, Canada | 1201 | PC | DEP | ANX | DSM‐III‐R | ORb | 11 | |
Newman, 1996, New Zealand | 1037 | PC | MOOD | ANX | DSM‐III‐R | ORb | ‐ | 10 |
Ohayon, 2000, Canada | 2516 | CS | DEP, BIPOLAR | GAD, AGO, PD, SO, SP, OCD, PTSD | DSM‐IV | ORb | ‐ | 11 |
Ohayon, 2010, Multiple countries | 18 980 | CS | DEP | GAD, OCD, PTSD, AGO, PD, SP | DSM‐IV | OR | ‐ | 10 |
Pakriev, 1998, Russia | 855 | CS | DEP | SO, SP | ICD‐10 | OR | ‐ | 12 |
Pietrzak, 2012, USA | 34 653 | PC | DEP, DYS, BIPOLAR, MOOD | PTSD | DSM‐IV | aOR | Sociodemographic variables, mental disorders | 16 |
Pirkola, 2005, Finland | 6038 | CS | DEP | ANX | DSM‐IV | ORb | ‐ | 13 |
Preville, 2008, Canada | 2798 | CS | DEP | GAD, AGO | DSM‐IV | ORb | ‐ | 12 |
Prina, 2011, Multiple countries | ‐d | CS | DEP | ANX | ICD‐10 | ORb | ‐ | 13 |
Rihmer, 2001, Hungary | 2953 | CS | DEP, BIPOLAR | GAD, PD, AGO, SO, SP | DSM‐III‐R | ORb | ‐ | 10 |
Ritchie, 2013, Francec | 1968 | PC | DEP | AGO | DSM‐IV | ORb | ‐ | 12 |
Rohde, 1991, USA | 3770 | PC | DEP | ANX | DSM‐III‐R | OR | ‐ | 13 |
Romano, 2005, Canada | 2000 | PC | DEP | ANX | DSM‐III‐R | OR | ‐ | 13 |
Roy‐Byrne, 2000, USA | 8098 | CS | DEP | PD | DSM‐III‐R | OR | ‐ | 14 |
Rueda‐Jaimes, 2008, Colombia | 474 | CS | DEP | OCD | DSM‐IV | OR, aOR | Did not specify | 15 |
Ruscio, 2008, USA | 9282 | CS | DEP, DYS, BIPOLAR, MOOD | SO | DSM‐III, DSM‐IV | aOR | Age, sex, race | 15 |
Ruscio, 2010, USA | 9282 | CS | DEP, DYS, BIPOLAR, MOOD | OCD | DSM‐IV | aOR | Age, sex, race | 15 |
Sahoo, 2010, India | 500 | CS | DEP | ANX | DSM‐IV, ICD‐10 | ORb | ‐ | 12 |
Sartorius, 1996, Multiple countries | 5438 | CS | DEP | ANX | ICD‐10 | OR | ‐ | 11 |
Schaffer, 2006, Canada | 36 984 | CS | BIPOLAR | ANX | DSM‐IV | OR | ‐ | 14 |
Schaub, 2000, Germany | 516 | CS | DEP | ANX | DSM‐III‐R | OR | ‐ | 12 |
Schneier, 1992, USA | 13 537 | CS | DEP, DYS, BIPOLAR | SO | DSM‐III | aOR | Age, sex, site | 15 |
Schoevers, 2003, the Netherlands | 4051 | PC | DEP | GAD | GMS‐AGECAT | ORb | ‐ | 11 |
Schrier, 2012, the Netherlands | 725 | CS | DEP | ANX | DSM‐IV | ORb | ‐ | 12 |
Scott, 2006, New Zealand | 12 992 | CS | DEP, DYS, BIPOLAR | PD, AGO, SP, SO, GAD, PTSD, OCD | DSM‐IV | OR | ‐ | 12 |
Serrano‐Blanco, 2010, Spain | 3820 | CS | DEP, DYS | SO, SP, AGO, PD | DSM‐IV | OR | ‐ | 14 |
Sicras‐Mainar, 2008, Spain | 65 767 | PC | DEP | GAD | ICD‐9 | aOR | Age, sex, mental disorders | 14 |
Spaner, 1994, Canada | 3258 | CS | DEP | OCD, PD, PHOBIA | DSM‐III | ORb | ‐ | 11 |
Stein, 2004, Canada | 9953 | CS | DEP | GAD | DSM‐III‐R | aOR | Age, sex, social class of parents, DYS | 15 |
Stylianidis, 2014, Greece | 900 | CS | DEP | GAD, PD, AGO | ICD‐10 | ORb | ‐ | 11 |
Subramaniam, 2013, Singapore | 6616 | CS | BIPOLAR | GAD, OCD | DSM‐IV | aOR | Age, sex, race | 16 |
Szadoczky, 2002, Hungary | 2953 | CS | DEP | PD, GAD, AGO, SO, SP, OCD, ANX | DSM‐III‐R | OR | ‐ | 14 |
Thompson, 1989, Canada | 3258 | CS | DEP | AGO, PD | DSM‐III | OR | ‐ | 13 |
Trumpf, 2010, Germany | 1538 | PC | DEP, MOOD | SP | DSM‐IV | OR, aOR | Mental disorders | 15 |
Tsuchiya, 2009, Japanc | 2437 | CS | DEP | SO, AGO, SP | DSM‐IV | aOR | Sex, birth‐cohort, number of other ANXs, marital status, education | 15 |
Vaiva, 2008, France | 36 105 | CS | DEP, DYS | PTSD | DSM‐IV | aOR | Variables that were significant in the univariate model | 12 |
Van Ameringen, 2008, Canada | 2991 | CS | DEP | PTSD | DSM‐IV | OR | ‐ | 13 |
van Balkom, 2000, the Netherlands | 3107 | PC | DEP | GAD, OCD, PD, PHOBIA | DSM‐III | OR | ‐ | 13 |
van Loo, 2016, the Netherlands | 167 729 | PC | DEP | GAD | DSM‐IV | OR | ‐ | 13 |
Weissman, 1994, Multiple countries | ‐d | CS, PC | DEP | OCD | DSM‐III | OR | ‐ | 13 |
Weissman, 1996, Multiple countries | ‐d | CS, PC | DEP | OCD, PD | DSM‐III | aOR | Age, sex | 13 |
Weissman, 1997, Multiple countries | 1746 | PC | DEP | PD | DSM‐III | aOR | Age, sex | 13 |
Wichstrom, 2012, Norway | 2475 | CS | DEP | ANX | DSM‐IV | OR | 14 | |
Wittchen, 1992, Germany | 1974 | PC | MOOD | ANX | DSM‐III | ORb | ‐ | 11 |
Wittchen, 1994, USA | 8098 | CS | DEP, DYS | GAD | DSM‐IV | OR | ‐ | 13 |
Wittchen, 1999, Germany | 3021 | PC | DEP, DYS, MOOD | SO | DSM‐IV | aOR | Sex | 14 |
Wittchen, 2000, Germany | 4181 | CS | DEP | GAD | DSM‐IV | ORb | ‐ | 12 |
Zhang, 2015, France | 2189 | CS | DEP | GAD | DSM‐IV | OR, aOR | Age, sex, mental disorders | 16 |
Zutshi, 2006, India | 130 | CC | BIPOLAR | GAD, OCD, SO, ANX | DSM‐IV | ORb | ‐ | 10 |
Abbreviations: AGO, agoraphobia with or without panic disorder; ANX, broadly defined anxiety disorder; aOR, adjusted odds ratio; BIPOLAR, bipolar I, II or bipolar disorder; CC, case‐control studies; CS, cross‐sectional studies; DEP, depressive disorder; DYS, dysthymia; GAD, generalized anxiety disorder; MOOD, mood disorder; OCD, obsessive‐compulsive disorder; OR, odds ratio; OVRANX, overanxious disorder; PC, prospective cohort studies; PD, panic disorder; PHOBIA, phobia disorder; PTSD, posttraumatic stress disorder; RR, risk ratio; SAD, separation anxiety disorder; SO, social phobia or social anxiety disorder; SP, specific phobia or simple phobia.
Disorders assessed in the study. We did not extract comorbidity estimates within the same disorder class.
These are extracted from 2 × 2 table.
These studies have both temporally and non‐temporally ordered estimates.
Multiple sample sizes.