Figure 2.

Patient disposition. ^aThere were 43 reasons for exclusion, and an individual patient could be excluded for multiple reasons. The main reasons for exclusions were the following: underlying pathology of sleep identified during the screening polysomnography (PSG) night, N = 116; Mini‐Mental State Exam outside the 12 to 26 range, N = 19; total sleep time (TST) >6.5 hours during the screening PSG night, N = 19; and mean TST over the screening and baseline PSG nights >6 hours, N = 15. ^bThe number of patients in the full‐analysis‐set for the primary endpoint of change from baseline in TST at week 4. In the suvorexant group, seven patients were excluded due to missing PSG data. In the placebo group, two patients were excluded due to missing PSG data and two patients were excluded due to Good Clinical Practice noncompliance issues at one site