Table 1.
(A) | |||||||
---|---|---|---|---|---|---|---|
Patients | All (n = 73) | WM (n = 69) | MEG-SII (n = 39) | ||||
Norm. | Abnorm. | p value | Norm. | Abnorm. | p value | ||
n/total (n, %) | 73 | 43/69 (62%) | 26/69 (38%) | 25/39 (64%) | 14/39 (36%) | ||
GA at birth (weeks; mean, SD) | 26.4 (1.2) | 26.5 (1.1) | 26.1 (1.3) | 0.216 | 26.5 (1.3) | 26.6 (1.0) | 0.727 |
Birth weight (g; mean, SD) | 867 (179) | 866 (175) | 868 (190) | 0.955 | 855 (175) | 936 (185) | 0.182 |
SGA, <2 SD (n, %) | 15 (21%) | 10 (23%) | 4 (15%) | 0.213 | 8 (32%) | 2 (14%) | 0.163 |
Male (n, %) | 46 (63%) | 22 (51%) | 21 (81%) | 0.014 | 10 (40%) | 10 (71%) | 0.062 |
Twin (n, %) | 17 (23%) | 7 (16%) | 9 (35%) | 0.082 | 5 (20%) | 4 (29%) | 0.554 |
Umbilical artery pH (mean, SD) | 7.29 (0.08) | 7.29 (0.06) | 7.27 (0.11) | 0.442 | 7.30 (0.06) | 7.31 (0.06) | 0.657 |
1-min Apgar (score; median, CI) | 5 (4.5–5.5) | 5 (4.4–5.6) | 3 (2.0-4.0) | 0.067 | 5 (5.1–5.9) | 6 (5.0–7.0) | 0.54 |
5-min Apgar (score; median, CI) | 7 (6.5–7.5) | 7 (6.5–7.5) | 6 (5.1–6.9) | 0.081 | 6 (5.6–7.4) | 7 (6.0–8.0) | 0.381 |
10-min Apgar (score; median, CI) | 7 (6.7–7.3) | 7 (6.7–7.3) | 5 (4.5–5.5) | 0.053 | 7 (6.6–7.4) | 8 (7.4–8.6) | 0.159 |
Antenatal steroid(s) (n, %) | 72 (99%) | 43 (100%) | 25 (96%) | 0.289 | 25 (100%) | 14 (100%) | — |
Postanal steroid (n, %) | 23 (32%) | 12 (28%) | 11 (42%) | 0.175 | 6 (24%) | 4 (29%) | 0.481 |
Surfactant (n, %) | 73 (100%) | 43 (100%) | 26 (100%) | — | 25 (100%) | 14 (100%) | — |
RDS (n, %) | 52 (71%) | 28 (65%) | 23 (88%) | 0.033 | 18 (72%) | 7 (50%) | 0.178 |
BPD at 36+0 GW (n, %) | 33 (45%) | 17 (40%) | 15 (58%) | 0.073 | 9 (36%) | 6 (43%) | 0.683 |
IVH, any (n, %) | 30 (41%) | 11 (26%) | 18 (69%) | 0.001 | 9 (36%) | 4 (29%) | 0.647 |
IVH, grades III–IV (n, %) | 13 (18%) | 2 (5%) | 11 (42%) | 0.001 | 4 (16%) | 2 (14%) | 0.89 |
Sepsis, (n, %) | 37 (51%) | 19 (44%) | 16 (62%) | 0.426 | 8 (32%) | 5 (36%) | 0.718 |
NEC (n, %) | 6 (8%) | 2 (5%) | 3 (12%) | 0.584 | 2 (8%) | 1 (7%) | 0.71 |
ROP (n) | 22 (30%) | 11 (26%) | 10 (38%) | 0.179 | 6 (24%) | 2 (14%) | 0.484 |
(B) | ||||||
---|---|---|---|---|---|---|
Patients | Hempel (n = 66) | GMDS (DQ) (n = 58) | ||||
Norm. | Abnorm. | p value | Norm. | Abnorm. | p value | |
n/total (n, %) | 26/66 (39%) | 40/66 (61%) | 34/58 (59%) | 24/58 (41%) | ||
GA at birth (weeks; mean, SD) | 26.3 (1.2) | 26.4 (1.2) | 0.682 | 26.5 (1.1) | 26.1 (1.2) | 0.252 |
Birth weight (g; mean, SD) | 869 (178) | 863 (195) | 0.897 | 869 (174) | 819 (184) | 0.3 |
SGA, <2 SD (n, %) | 5 (19%) | 9 (23%) | 0.645 | 9 (26%) | 5 (21%) | 0.778 |
Male (n, %) | 13 (46%) | 30 (75%) | 0.017 | 19 (56%) | 16 (67%) | 0.417 |
Twin (n, %) | 9 (35%) | 7 (18%) | 0.116 | 9 (26%) | 3 (13%) | 0.202 |
Umbilical artery pH (mean, SD) | 7.29 (0.06) | 7.29 (0.09) | 0.897 | 7.28 (0.06) | 7.3 (0.11) | 0.366 |
1-min Apgar (score; median, CI) | 4 (3.2–4.8) | 5.5 (4.8–6.2) | 0.968 | 5 (4.3–5.7) | 5.5 (4.6–6.4) | 0.97 |
5-min Apgar (score; median, CI) | 7 (6.2–7.8) | 7 (6.4–7.6) | 0.73 | 7 (6.3–7.7) | 6 (5.1–6.9) | 0.111 |
10-min Apgar (score; median, CI) | 7 (6.6–7.4) | 7 (6.6–7.4) | 0.817 | 7 (6.7–7.3) | 7 (6.5–7.5) | 0.967 |
Antenatal steroid(s) (n, %) | 26 (100%) | 40 (100%) | 0.485 | 34 (100%) | 24 (100%) | 0.982 |
Postanal steroid (n, %) | 10 (38%) | 10 (25%) | 0.485 | 11 (32%) | 7 (29%) | 0.897 |
Surfactant (n, %) | 26 (100%) | 40 (100%) | — | 34 (100%) | 24 (100%) | — |
RDS (n, %) | 20 (77%) | 27 (68%) | 0.417 | 27 (79%) | 14 (58%) | 0.085 |
BPD at 36+0 GW (n, %) | 15 (58%) | 17 (43%) | 0.234 | 16 (47%) | 13 (54%) | 0.601 |
IVH, any (n, %) | 10 (38%) | 15 (38%) | 0.938 | 12 (35%) | 7 (29%) | 0.632 |
IVH, grades III–IV (n, %) | 2 (8%) | 9 (23%) | 0.118 | 3 (9%) | 4 (17%) | 0.375 |
Sepsis (n, %) | 13 (50%) | 21 (53%) | 0.41 | 16 (47%) | 15 (63%) | 0.234 |
NEC (n, %) | 1 (4%) | 5 (13%) | 0.486 | 2 (6%) | 2 (8%) | 0.737 |
ROP (n) | 5 (19%) | 16 (40%) | 0.079 | 7 (21%) | 11 (46%) | 0.041 |
Data are presented as n (%) or mean (SD) or median (95% CI).
Statistically significant p-values are in bold.