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. 2021 Mar 22;16(3):e0246157. doi: 10.1371/journal.pone.0246157

Table 5. Sex distribution of multiple sclerosis cases reported prior to 1922*.

Europe (Historical) United States (Historical) United States (Wechsler Series) Total
Men 658 (58%) 99 (60%) 117 (59%) 874 (58%)
Women 484 (42%) 67 (40%) 80 (41%) 631 (42%)
Total 1,142 (100%) 166 (100%) 197 (100%) 1,505 (100%)

* Data from: Wechsler IS [66]. Historical cases were reported in the medical literature, for the most part, prior to 1903, whereas Wechsler’s series was drawn from the Mount Sinai Hospital, the Montefiore Hospital, and the Vanderbilt Clinic (1912–1921).