FIG. 2.

Representative ADPase-stained retinas from rats exposed to neonatal IH at postnatal day 21 (P21) and treated with topical ocular or oral saline or propranolol. The upper panels are peripheral vessels, and the lower panels are vessels at the optic disk. Pups were administered a single daily treatment of topical ocular or oral propranolol or saline occurred from P5 to P14. Saline treatment in neonatal IH resulted in hemorrhage, vessel tortuosity, vascular abundance, and neovascularization (arrows) which were not prevented with propranolol (arrows). Images are 10 × magnification, scale bar is 100 μm. IH, intermittent hypoxia. Color images are available online.