FIG. 4.

Representative GFAP (green)/isolectin B (red)-stained retinas from rats exposed to neonatal IH at postnatal day 21 (P21) and treated with topical ocular or oral saline or propranolol. The upper panels are peripheral vessels, and the lower panels are vessels at the optic disk. Pups were administered a single daily treatment of topical ocular or oral propranolol or saline occurred from P5 to P14. Saline treatment in neonatal IH caused astrocyte damage and gliosis (arrows) which was prevented with propranolol treatment. Images are 10 × magnification, scale bar is 100 μm. Color images are available online.