Representative H&E-stained retinas from rats raised in RA (upper panels) or neonatal IH (lower panels) at postnatal day 21 (P21) and treated with topical ocular or oral saline or propranolol. Pups were administered a single daily treatment of topical ocular or oral propranolol or saline occurred from P5 to P14. Saline treatment in neonatal IH increased NFL/GCL layer and number of endothelial cells, as did propranolol treatment in RA and neonatal IH (arrows). Images are 40 × magnification, scale bar is 20 μm. H&E, Hematoxylin and Eosin; INL, inner nuclear layer; IPL, inner plexiform layer; NFL/GCL, nerve fiber layer/ganglion cell layer; ONL, outer nuclear layer; R/C, rods and cones. Color images are available online.