Table 2.
RA |
IH |
|||||||
---|---|---|---|---|---|---|---|---|
Topical ocular |
Oral |
Topical ocular |
Oral |
|||||
Sal | Prop | Saline | Prop | Saline | Prop | Saline | Prop | |
% Change body wt. (P0–P21) | 350.1 ± 14.4 | 429.1 ± 14.5** | 475.1 ± 32.4## | 482.3 ± 7.2## | 514.0 ± 11.6§§ | 532.0 ± 22.1§§ | 388.0 ± 21.3##§§ | 458.6 ± 11.3**## |
% Change length (P0–P21) | 84.6 ± 1.4 | 95.2 ± 4.1* | 97.4 ± 3.6## | 99.7 ± 1.2 | 84.1 ± 2.2 | 84.9 ± 2.2§ | 73.1 ± 1.8##§§ | 79.1 ± 1.2#§§ |
Brain/body wt. ratio | 0.041 ± 0.001 | 0.034 ± 0.001** | 0.034 ± 0.002## | 0.03 ± 0.0006 | 0.052 ± 0.001§§ | 0.056 ± 0.001§§ | 0.039 ± 0.001## | 0.034 ± 0.0009**## |
Heart/Body wt. ratio | 0.006 ± 0.004 | 0.006 ± 0.0003 | 0.005 ± 0.0002 | 0.006 ± 0.0006 | 0.01 ± 0.0003§§ | 0.01 ± 0.004§§ | 0.007 ± 0.0003## | 0.005 ± 0.0002**## |
Lung/body wt. ratio | 0.01 ± 0.0004 | 0.01 ± 0.0005 | 0.01 ± 0.001 | 0.01 ± 0.0005 | 0.019 ± 0.0002§§ | 0.019 ± 0.005§§ | 0.013 ± 0.0003## | 0.012 ± 0.0004## |
Liver/body wt. ratio | 0.034 ± 0.002 | 0.037 ± 0.002 | 0.039 ± 0.002 | 0.03 ± 0.002*# | 0.067 ± 0.003 | 0.061 ± 0.003§§ | 0.035 ± 0.002##§§ | 0.034 ± 0.001## |
Kidney/body wt. ratio | 0.013 ± 0.0006 | 0.012 ± 0.0006 | 0.012 ± 0.0006 | 0.013 ± 0.0002 | 0.021 ± 0.0006§§ | 0.019 ± 0.0005*§§ | 0.011 ± 0.0006## | 0.012 ± 0.0004## |
P < 0.05, **P < 0.01 saline versus propranolol; #P < 0.05, ##P < 0.01 topical ocular versus oral §P < 0.05, §§P < 0.01 RA vs. IH (n = 18 pups/group).