Table 5.

Retinal Morphometry: P14

	RA				IH
	Topical ocular		Oral		Topical ocular		Oral
	Saline	Prop	Saline	Prop	Saline	Prop	Saline	Prop
Corneal thickness, μm	142.0 ± 24.3	106.8 ± 8.0	109.8 ± 12.8	122.3 ± 22.1	146.8 ± 13.9	161.8 ± 31.9	122.3 ± 25.4	116.3 ± 12.1
	n = 12	n = 18**	n = 12##	n = 21##	n = 16	n = 10§§	n = 12##	n = 12##
No. corneal epithelial cells	405.8 ± 9.7	162.6 ± 7.6	304.6 ± 18.5	180.9 ± 12.2	255.3 ± 24.3	171.2 ± 7.8	297.0 ± 16.9	187.9 ± 8.7
	n = 12	n = 18**	n = 12##	n = 21**##	n = 16§§	n = 10**	n = 12	n = 12**
Tortuosity index	0.97 ± 0.02	0.96 ± 0.03	0.95 ± 0.03	0.94 ± 0.03	0.95 ± 0.02	0.94 ± 0.03	0.95 ± 0.03	0.95 ± 0.03
	n = 11	n = 19	n = 16	n = 21	n = 19	n = 18	n = 5	n = 18
Artery diameter, μm	25.5 ± 4	24.4 ± 3.8	27.9 ± 3.8	24 ± 3.6	29 ± 6.2	22.2 ± 4.5	30.5 ± 8.2	25.5 ± 6.3
	n = 20	n = 23	n = 24	n = 30	n = 28	n = 23	n = 13	n = 24
Vein diameter, μm	34.6 ± 8.1	36.3 ± 9.7	35.9 ± 8.3	38.2 ± 9.7	36.8 ± 8.3	34.8 ± 7	29.2 ± 4.6	34 ± 5.6
	n = 21	n = 21	n = 24	n = 27	n = 20	n = 20	n = 9	n = 18
Neovascularization	1063.7 ± 263.5	2126.1 ± 619.1**	1354.0 ± 273.6	2013.6 ± 827.7*	3112.3 ± 890.2§§	1661.3 ± 345.8**	2176.6 ± 803.4##§§	1661.9 ± 237.3*
Number cells in NFL/GCL	210 ± 73	194 ± 38	348 ± 80	412 ± 169	148.7 ± 54.5	307.2 ± 26.1	298.2 ± 93	241.3 ± 61.6
	n = 4	n = 6	n = 4	n = 6	n = 3	n = 4*	n = 4	n = 6
Total retinal thickness, μm	292.5 ± 14	274.3 ± 51.7	305.9 ± 33.2	240 ± 31	229.8 ± 14.3	468.9 ± 11.3	561 ± 50	314 ± 46.9
	n = 4	n = 10	n = 6	n = 8	n = 4	n = 4**§	n = 4##§§	n = 6**
NFL/GCL thickness, μm	41.2 ± 7	34.5 ± 12.2	44.5 ± 7.5	32.4 ± 4.7	37.8 ± 7.6	68.1 ± 7.9	82.3 ± 21.2	50.4 ± 7.2
	n = 4	n = 10	n = 6	n = 8	n = 4	n = 4*	n = 4	n = 6§
IPL thickness, μm	38.8 ± 6	41.6 ± 10.9	50 ± 8.7	40.1 ± 2.6	41.2 ± 5.4	93.6 ± 4.3	73.9 ± 5.6	58.7 ± 10
	n = 4	n = 10	n = 6	n = 8	n = 4	n = 4**§§	n = 4	n = 6#
INL thickness, μm	67.4 ± 7.8	65.8 ± 15.9	60.4 ± 13.9	50.1 ± 3.4	47.4 ± 9	110.1 ± 2.2	128.8 ± 9.4	77.6 ± 12.7
	n = 4	n = 10	n = 6	n = 8	n = 4	n = 4**	n = 4##§§	n = 6**§
ONL thickness, μm	101.5 ± 11.4	94.1 ± 12.8	95.3 ± 4.5	77.5 ± 14.8	75.4 ± 7.6	109.8 ± 12.6	163.5 ± 14.1	98 ± 9.8
	n = 4	n = 10	n = 6	n = 8	n = 4	n = 4*	n = 4##§§	n = 6**

Data are mean ± SD. One-way ANOVA with Bonferroni's post hoc test was used to compare data among the topical ocular or oral groups. Unpaired t-test was used to compare RA versus IH.

^*P < 0.05, ^**P < 0.01 saline versus propranolol; ^#P < 0.05, ^##P < 0.01 topical ocular versus oral; ^§P < 0.05, ^§§P < 0.01 RA versus IH.

INL, inner nuclear layer; IPL, inner plexiform layer; NFL/GCL, nerve fiber layer/ganglion cell layer; ONL, outer nuclear layer; SD, standard deviation.