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. 2021 Mar 4;37(2):112–130. doi: 10.1089/jop.2020.0092

Table 6.

Retinal Morphometry – P21

  RA
 IH
Topical ocular
 Oral
 Topical ocular
 Oral
Saline Prop Saline Prop Saline Prop Saline Prop
Corneal thickness, μm 166.4 ± 9.9 190.5 ± 8.1 154.3 ± 4.3 137.5 ± 4.0 144.7 ± 13.5 151.1 ± 28.5 138.0 ± 13.5 130.6 ± 5.9
n = 10 n = 10** n = 10## n = 10**## n = 16§§ n = 10§§ n = 16§§ n = 10#§§
No. corneal epithelial cells 244.5 ± 39.1 281.6 ± 35.8 256.0 ± 11.3 271.4 ± 11.9 387.1 ± 29.5 301.9 ± 9.3 445.6 ± 13.2 245.6 ± 13.4
n = 10 n = 10* n = 10 n = 10** n = 16§§ n = 10** n = 12##§§ n = 10##§
Tortuosity index 0.96 ± 0.02 0.97 ± 0.028.1 0.91 ± 0.06 0.97 ± 0.03 0.94 ± 0.04 0.97 ± 0.009 0.92 ± 0.03 0.95 ± 0.03
n = 28 n = 21 n = 8 n = 19 n = 17 n = 10 n = 22 n = 22
Artery diameter, μm 27.5 ± 6 25.7 ± 7 23.2 ± 5.4 26.6 ± 6.6 30.6 ± 4.9 29.5 ± 8.1 29.4 ± 4.5 30.9 ± 6.4
n = 46 n = 27 n = 15 n = 24 n = 34 n = 25 n = 38 n = 36
Vein diameter, μm 37.1 ± 7.4 40.2 ± 7.8 38.8 ± 7.9 36.5 ± 7.5 36.7 ± 8.6 37 ± 5.6 41.1 ± 8.7 38 ± 5.8
n = 39 n = 22 n = 12 n = 22 n = 21 n = 15 n = 32 n = 23
Neovascularization 1820.7 ± 823.5 1376.8 ± 258.7 1249.9 ± 504.5 1422.9 ± 348.5 2560.1 ± 364.2§ 1979.6 ± 463.5**§§ 2208.8 ± 419.8§§ 1790.0 ± 362.6*
Number of cells in NFL/GCL 145.3 ± 45.7 179.6 ± 59.8 168 ± 36.9 208.5 ± 39 173 ± 109 172.3 ± 56.2 134.7 ± 52.8 174.5 ± 44.9
n = 3 n = 3 n = 5 n = 6 n = 9 n = 9 n = 9 n = 9
Total retinal thickness, μm 306.7 ± 43.1 350.5 ± 27.4 341.7 ± 63.4 335.3 ± 63.2 296.8 ± 48.8 322.9 ± 96.7 297.9 ± 55 292. ± 42.3
n = 6 n = 4 n = 8 n = 12 n = 6 n = 6 n = 8 n = 8
NFL/GCL thickness, μm 39.1 ± 1.5 52.4 ± 18.8 37.8 ± 7.2 38.4 ± 9.2 33 ± 10.9 33 ± 6.2 38.2 ± 4.2 32.8 ± 6.3
n = 6 n = 4 n = 8 n = 12 n = 6 n = 6 n = 8 n = 8
IPL thickness, μm 47.3 ± 8.7 62 ± 6.7 68.8 ± 14.1 73.8 ± 18.2 56.6 ± 13.2 64.1 ± 19.4 69.7 ± 18 52 ± 7.7
n = 6 n = 4 n = 8 n = 12 n = 6 n = 6 n = 8 n = 8
INL thickness, μm 56.5 ± 10.1 64.5 ± 1.5 66 ± 14.9 72.7 ± 16.3 53.7 ± 12.3 67.9 ± 25.5 48 ± 23 51.3 ± 8.7
n = 6 n = 4 n = 8 n = 12 n = 6 n = 6 n = 8 n = 8
ONL thickness, μm 90.4 ± 19.2 93.5 ± 3.2 95.9 ± 17.5 100.2 ± 15.8 91.8 ± 13.6 96.5 ± 24.8 83.4 ± 30.9 82.7 ± 12.8
n = 6 n = 4 n = 8 n = 12 n = 6 n = 6 n = 8 n = 8

Data are mean ± SD. One-way ANOVA with Bonferroni's post hoc test was used to compare data among the topical ocular or oral groups. Unpaired t-test was used to compare RA versus IH.

*

P < 0.05; **P < 0.01 saline versus propranolol; #P < 0.05; ##P < 0.01 topical ocular versus oral; §P < 0.05, §§P < 0.01 RA versus IH.