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. 2016 Sep;37(9):1664–1668. doi: 10.3174/ajnr.A4827

Table 2:

Risk factors for intracranial aneurysms in patients with aortic aneurysms

All
AAA Only
TAA Only
TAA and AAA
OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P
Age (1-yr increase) 0.99 (0.91–1.08) .29 0.99 (0.95–1.04) .61 1.00 (0.97–1.03) .61 0.96 (0.92–0.98) .01
AAA size (mm increase) 1.02 (1.01–1.03) .045 1.01 (0.96–1.07) .36 1.04 (1.02–1.06) .03
TAA size (mm increase) 1.01 (0.97–1.04) .49 1.00 (0.96–1.04) .83 1.02 (0.98–1.06) .14
Female sex 2.08 (1.49–3.03) .0002 1.31 (0.68–2.51) .42 2.32 (1.26–4.26) .006 4.74 (1.95–11.50) .0002
Comorbidities
    Stroke/TIA 0.83 (0.58–1.20) .035 0.61 (0.35–1.07) .08 1.40 (0.76–2.57) .27 0.51 (0.21–1.21) .12
    CAD 0.68 (0.47–0.99) .047 0.63 (0.37–1.11) .11 0.40 (0.18–0.92) .03 0.97 (0.41–2.28) .94
    HTN 0.93 (0.60–1.46) .76 0.64 (0.28–1.46) .29 0.96 (0.51–1.77) .88 1.06 (0.23–4.94) .94
    DM 0.85 (0.52–1.39) .52 0.70 (0.36–1.38) .34 0.43 (0.13–1.45) .16 2.30 (0.87–6.08) .13
    HLP 0.82 (0.55–1.20) .31 0.41 (0.21–0.78) .006 1.26 (0.69–2.30 .54 0.63 (0.25–1.58) .32
Bicuspid aortic valve 0.72 (0.40–1.32) .33 NA .84 0.59 (0.29–1.23) .16 5.96 (1.25–28.50) .01
Current/former smoker 1.25 (0.86–1.84) .24 0.82 (0.47–1.45) .57 0.94 (0.40–2.20) .89 3.90 (1.58–9.64) .002

Note:—CAD indicates carotid artery disease; HTN, hypertension; DM, diabetes mellitus; HLP, hyperlipidemia; NA, not applicable.