Table 3.

Clinical, biochemical, and radiological variables before-and-after treatment in ozone group and standard of care group

Variables	Ozone before (n=14)	Ozone after (n=14)	p	Standard of care before (n=14)	Standard of care after (n=14)	p
Clinical variables
O2 saturation %	94.3 ± 0.94	94.5 ± 2.09	0.6682	92.96 ± 0.42	92.9 ± 0.12	0.9389
O2 supply L/min	7.1 ± 6.31	3.5 ± 2.3	0.0930	4.4 ± 5.1	5.04 ± 6.1	0.7920
Biochemical variables
Leucocytes cells/mL	8602 ± 3676	7823 ± 2568	0.4165	6791 ± 3252	6058 ± 1950	0.5478
Lymphocytes cells/mL	985 ± 484	1278 ± 583	0.0403*	1616 ± 2350	1158 ± 503	0.5104
Fibrinogen mg/dL	713 ± 112	572 ± 163	0.0107*	602 ± 160	528 ± 149	0.3659
D-Dimer ng/mL	3240 ± 2484	1343 ± 1320	0.0110*	1153 ± 595	853 ± 330	0.0251*
Urea mg/dL	67 ± 41	55 ± 24	0.1089	73 ± 47	69 ± 41	0.5997
Ferritin ng/mL	989 ± 799	840 ± 1060	0.6043	861 ± 806	1028 ± 1219	0.3379
LDH U/L	329 ± 111	241 ± 89	0.0209*	262 ± 128	242 ± 84	0.0570
CRP mg/mL	8.9 ± 6.14	2.46 ± 3.78	0.0040*	6.5 ± 6.6	1.91 ± 2.3	0.0525
IL-6 pg/mL	85.07 ± 50.5	30.48 ± 38.1	0.0048*	44.2 ± 23.2	23.3 ± 17.3	0.2365
Radiological variables
Taylor scale	4.78 ± 0.42	3 ± 0.78	0.0000*	4.25 ± 0.75	3. .75 ± 0.96	0.3145

p, statistical Student T-test; L/min, liters per minute; LDH, lactate dehydrogenase; CRP, C-reactive protein. *p<0.05