Table 2.
Top 10 up- and downregulated DEmRNAs.
| Symbol | log2FC | p value | FDR | Regulation |
|---|---|---|---|---|
| OA vs. control | ||||
| HIST2H4A | 2.017903 | 1.45E-12 | 1.86E-08 | Up |
| ZNF778 | 2.30578 | 2.34E-09 | 1.50E-05 | Up |
| RAB8A | 1.084187 | 4.61E-07 | 0.001473 | Up |
| MYOM2 | 3.614517 | 1.16E-05 | 0.021164 | Up |
| PI3 | 1.77021 | 4.16E-05 | 0.05915 | Up |
| VASH1 | 1.031837 | 0.000207 | 0.203576 | Up |
| SNHG28 | 1.440766 | 0.000309 | 0.263506 | Up |
| LILRB3 | 1.133152 | 0.000349 | 0.27883 | Up |
| UPRT | 1.107994 | 0.000428 | 0.322295 | Up |
| UNC13B | 1.407436 | 0.000467 | 0.331741 | Up |
| CD8A | -1.49304 | 2.03E-07 | 0.000865 | Down |
| AL157935.2 | -3.11394 | 2.71E-06 | 0.006946 | Down |
| AL121594.1 | -3.12822 | 4.34E-06 | 0.00926 | Down |
| EPHB4 | -2.33741 | 1.40E-05 | 0.022395 | Down |
| F11R | -1.30037 | 6.96E-05 | 0.080899 | Down |
| YPEL2 | -1.41993 | 0.000184 | 0.196205 | Down |
| CHKB-CPT1B | -1.48977 | 0.00028 | 0.255821 | Down |
| ZNF80 | -1.53824 | 0.000671 | 0.393542 | Down |
| EEF1AKMT3 | -1.76553 | 0.000677 | 0.393542 | Down |
| CD8B | -1.42735 | 0.000767 | 0.426828 | Down |
| Osteolysis vs. control | ||||
| ZNF778 | 2.261961 | 6.77E-08 | 0.000222 | Up |
| LILRB3 | 1.396428 | 1.23E-06 | 0.003224 | Up |
| MYOM2 | 3.476227 | 3.33E-06 | 0.00575 | Up |
| BCORL1 | 2.051727 | 1.40E-05 | 0.018296 | Up |
| RTL5 | 1.812327 | 1.85E-05 | 0.022092 | Up |
| FOSL2 | 1.834524 | 3.50E-05 | 0.026994 | Up |
| CNTNAP3 | 2.346929 | 7.26E-05 | 0.047612 | Up |
| MGAM2 | 2.714451 | 9.47E-05 | 0.049807 | Up |
| ERV3-1 | 1.398861 | 9.50E-05 | 0.049807 | Up |
| TMEM164 | 1.378476 | 0.000107 | 0.053473 | Up |
| TMEM56-RWDD3 | -3.54683 | 9.81E-12 | 1.29E-07 | Down |
| AC013489.1 | -4.17415 | 3.51E-06 | 0.00575 | Down |
| PLVAP | -2.61008 | 2.39E-05 | 0.026097 | Down |
| PPDPF | -2.88183 | 2.75E-05 | 0.026397 | Down |
| RPS26 | -2.22182 | 2.82E-05 | 0.026397 | Down |
| HBB | -2.40451 | 3.29E-05 | 0.026994 | Down |
| RGS6 | -2.33305 | 4.89E-05 | 0.035625 | Down |
| EVPL | -3.08781 | 5.28E-05 | 0.036452 | Down |
| RIOK3 | -2.15799 | 7.94E-05 | 0.049573 | Down |
| LRRN3 | -2.13595 | 8.98E-05 | 0.049807 | Down |
| Osteolysis vs. OA | ||||
| EPHB4 | 3.187856 | 9.59E-07 | 0.003135 | Up |
| RASSF5 | 1.444879 | 1.47E-05 | 0.023969 | Up |
| FAM118A | 1.406201 | 4.97E-05 | 0.064931 | Up |
| AL354822.1 | 2.9104 | 0.000364 | 0.250326 | Up |
| AL121594.1 | 2.129941 | 0.0004 | 0.259591 | Up |
| ZNF587 | 1.181929 | 0.000736 | 0.320854 | Up |
| SERPING1 | 1.589099 | 0.002698 | 0.608048 | Up |
| LRP1 | 1.363794 | 0.004148 | 0.796847 | Up |
| CASP10 | 1.098776 | 0.004527 | 0.796847 | Up |
| REC8 | 1.074025 | 0.004665 | 0.796847 | Up |
| MTURN | -1.58117 | 1.09E-05 | 0.021921 | Down |
| HBB | -2.3627 | 1.17E-05 | 0.021921 | Down |
| CISD2 | -1.29668 | 6.10E-05 | 0.07251 | Down |
| AC093668.3 | -2.78122 | 6.93E-05 | 0.073252 | Down |
| DDA1 | -1.3542 | 8.91E-05 | 0.08323 | Down |
| AC013489.1 | -3.94451 | 0.000133 | 0.11567 | Down |
| ARL4A | -1.83919 | 0.00018 | 0.147286 | Down |
| EPB41 | -1.62564 | 0.000288 | 0.221659 | Down |
| CR1L | -1.61874 | 0.000353 | 0.250326 | Down |
| DLGAP5 | -2.34576 | 0.000426 | 0.259591 | Down |
FC: fold change; FDR: false discovery rate; OA: osteoarthritis.