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IL-22 treatment inhibited the inflammatory response after cerebral I/R injury. Serum levels of IL-1β (a), MCP-1 (b), and TNF-α (c) were measured by ELISA (n = 8). The mRNA expression of IL-1β (d), MCP-1 (e), and TNF-α (f) was detected in brain tissues (n = 8). ∗P < 0.05 vs. sham group; #P < 0.05 vs. MCAO group.
