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. 2021 Mar 15;2021:8896108. doi: 10.1155/2021/8896108

Figure 3.

Figure 3

Effect of paquinimod on goblet cell count and lung resistance of OVA/CFA-treated mice. (a) Percentage of goblet cells in bronchial epithelium; periodic acid-Schiff (PAS)-positive cells and total epithelial cells were counted in the epithelium and the percentage of PAS-positive cells was calculated (n = 8 in each group). (b) Lung resistance of sham-treated or OVA/CFA-treated mice and OVA/CFA plus paquinimod (0.1 mg/kg/day to 25 mg/kg/day, p.o.) after challenges with increasing concentrations of methacholine (n = 8 in each group). ∗P < 0.05 compared with the sham group; #P < 0.05 compared with the OVA/CFA group. The P value was obtained using the Mann–Whitney U test.