Table 1.
Sociodemographic and Baseline Clinical Characteristics
| Characteristic | n (%) | Mean ± SD |
|---|---|---|
| Age | 21 (100) | 10.86 ± 2.88 |
| Sex | ||
| Male | 13 (62) | |
| Female | 8 (38) | |
| Race | ||
| White | 19 (90) | |
| Asian | 1 (5.0) | |
| Asian/White | 1 (5.0) | |
| Weight (kg) | 20 (95) | 43.83 ± 21.18 |
| PANS with streptococcal relationship | 14 (67) | |
| Years of PANS symptoms (before enrollment) | 4.3 ± 2.2 | |
| PANS Scale, OCD Symptom Score (0–25) | 19 (90) | 21.32 ± 5.22 |
| CY-BOCS total (0–40) | 21 (100) | 22.10 ± 7.82 |
| CGI-S | 4.67 ± 0.84 | |
| Moderate (4) | 10 (48) | |
| Marked (5) | 6 (28) | |
| Severe (6) | 5 (24) | |
| CaMKII | ||
| Serum | 21 (100) | 130.85 ± 25.01 |
| Elevated (>130) | 7 (33) | |
| Antitubulin antibodies | ||
| Serum | 21 (100) | 1880.95 ± 1252.66 |
| Elevated (≥1000) | 20 (95) | |
CaMKII, calcium/calmodulin-dependent protein kinase II; CGI-S, Clinical Global Impressions of Severity; CY-BOCS, Children's Yale-Brown Obsessive Compulsive Scale; OCD, obsessive compulsive disorder; PANS Scale, Pediatric Acute Neuropsychiatric Symptoms Scale; SD, standard deviation.