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. 2021 Mar 22;3(1):lqab015. doi: 10.1093/nargab/lqab015

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© The Author(s) 2021. Published by Oxford University Press on behalf of NAR Genomics and Bioinformatics.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Relationship between top imaging and gene features. Rectangle nodes are image features and circle nodes are gene features. Node sizes are proportional to importance scores from Cox-nnet. Two gene nodes are connected only if their correlation is > 0.5; an image node and a gene node are connected only if their correlation is > 0.1 (P-value < 0.05). Green nodes represent features with positive coefficients (hazard ratio) in univariate Cox-PH regression, indicating worse prognosis. Blue nodes represent features with negative coefficients (hazard ratio) in univariate Cox-PH regression, indicating protection against bad prognosis.