Table 2.
All adnexal | Sweat gland carcinoma | Hidradenocarcinoma | Spiradenocarcinoma | Sclerosing sweat duct tumor (MAC) | Porocarcinoma | Eccrineadenocarcinoma | Sebaceous carcinoma (n, %) | |
---|---|---|---|---|---|---|---|---|
Stage (derived AJCC stage group, 6th ed (2004–2015) | N = 1863 | N = 70 | N = 127 | N = 46 | N = 236 | N = 229 | N = 187 | N = 968 |
I (n, %) | 1221 (65.5) | 40 (57.1) | 56 (44.1) | 14 (30.4) | 150 (63.6) | 140 (61.1) | 103 (55.1) | 718 (74.2) |
II (n, %) | 440 (23.6) | 14 (20.0) | 54 (47.5) | 28 (60.9) | 47 (19.9) | 64 (27.9) | 51 (27.3) | 182 (18.8) |
III (n, %) | 155 (8.3) | 12 (17.1) | 11 (8.7) | 3 (6.5) | 38 (16.1) | 20 (8.7) | 28 (15.0) | 43 (4.4) |
IV (n, %) | 47 (2.5) | 4 (5.7) | 6 (4.7) | 1 (2.2) | 1 (0.4) | 5 (2.2) | 5 (2.7) | 25 (2.6) |
5-Year OS based on stage | ||||||||
I, OS (95% CI) | 79.0 (75.6–82.0) | 85.7 (61.7–95.2) | 91.1 (74.5–97.1) | 80.3 (69.9–85.4) | 87.7 (79.2–92.9) | 78.4 (67.5–86.1) | 80.2 (67.9–88.1) | 74.1 (69.0–78.5) |
II, OS (95% CI) | 74.4 (68.8–79.2) | 53.5 (21.2–77.7) | 80.9 (63.6–90.6) | 60.3 (35.3–78.2) | 85.0 (67.6–93.5) | 77.4 (60.9–87.6) | 72.4 (55.0–85.3) | 73.3 (63.7–80.7) |
III, OS (95% CI) | 67.4 (56.6–76.0) | 62.5 (22.9–86.1) | 53.3 (17.7–79.6) | – | 83.3 (61.0–93.4) | 52.9 (24.3–76.3) | 81.4 (52.8–93.6) | 53.2 (30.3–71.7) |
IV, OS (95% CI) | 17.1 (4.6–26.5) | – | – | – | – | – | – | 30.0 (7.1–57.8) |
5–Year DSS based on stage | ||||||||
I, DSS (95% CI) | 99.3 (98.2–99.7) | 100 (97.6–100) | 96.5 (94.0–98.2) | 97.9 (95.2–98.1) | 96.9 (90.4–99.0) | 97.4 (89.7–99.3) | 98.7 (91.2–99.8) | 99.0 (96.9–99.7) |
II, DSS (95% CI) | 97.8 (95.2–99.0) | 87.5 (38.7–98.1) | 94.1 (78.4–98.5) | 90.3 (66.3–97.5) | 93.3 (75.9–98.3) | 95.2 (87.3–96.7) | 93.9 (77.7–98.5) | 98.3 (93.5–99.6) |
III, DSS (95% CI) | 89.0 (79.894.2) | 71.4 (35.892.0) | 70.0 (22.591.8) | – | 83.3 (61.093.4) | 66.1 (31.686.2) | – | 79.8 (49.493.0) |
IV, DSS (95% CI) | 50.3 (18.575.7) | – | – | – | – | – | – | 53.7 (13.182.7) |
AJCC American Joint Committee on Cancer, OS overall survival, DSS disease-specific survival, CI confidence interval