TABLE 3.

Preclinical in vivo studies of hMSCs used as advanced therapy for burns in the last 5 years.

Type of Advanced Therapy	Cells	Type of hMSC treatment evaluated	Type of wound analyzed	Follow-up	References
Cell therapy	hWJ-MSCs	1-hWJ-MSC: 5 × 105 cells using cell spray method	Third degree burns	21 days	Pourfath et al., 2018
Tissue engineering	hDT-MSCs	1-hDT-MSCs + poly-D,L-lactic acid (PDLLA) + laminin-332 protein (lam): 105 cells + 105 keratinocytes + scaffold 2- hDT-MSCs + PDLLA: 105 cells + 105 keratinocytes + scaffold	Third degree burns	9 days	Steffens et al., 2017
	hUCB-MSCs	1-hUCB-MSC + plasma: 2.5 × 104 derived fibroblast cells + 3 × 104 derived keratinocyte cells + scaffold	Burn injury	20 days	Mahmood et al., 2019
	hAT-MSCs	1-Fresh hAT-MSCs: 5 × 104 cells on artificial dermis 2-Frozen hAT-MSCs: 5 × 104 cells on artificial dermis	Third degree burn wound	12 days	Kaita et al., 2019
	hWJ-MSCs	1-hWJ-MSC + acellular matrix: 2 × 106 hWJSCs seeded onto acellular dermal matrix scaffold	Third-degree burn	21 days	Nazempour et al., 2020