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. 2021 Mar 9;12:639857. doi: 10.3389/fphys.2021.639857

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Copyright © 2021 Zhang, Chen, Dong and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The involvement of Na⁺-K⁺-ATPase (NKA) in the EDH-mediated vasorelaxation of mesenteric arteries. (A) Summary data showing the CRC, R_max, and EC₅₀ of CPA-induced vasorelaxation in the presence of either L-NNA + INDO (n = 6) or L-NNA + INDO (&) + 100 μM ouabain (n = 6). (B) Summary data showing the CRC, R_max, and EC₅₀ of CPA-induced vasorelaxation in the presence of either L-NNA + INDO (n = 6) or L-NNA + INDO (&) + 0 K⁺ (n = 6). Data were expressed as percentage of NE (5 μM)-induced vasoconstrictions and shown as means ± SEM. ^***p < 0.001, and ns, no significance.