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. 2021 Mar 9;12:639857. doi: 10.3389/fphys.2021.639857

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Copyright © 2021 Zhang, Chen, Dong and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The involvement of sodium-calcium exchanger in the EDH-mediated vasorelaxation of mesenteric arteries.(A) Representative tracings of CPA-induced dose-dependent vasorelaxation in the presence of either L-NNA + INDO (the left panel) or L-NNA + INDO + 10 μM SN-6 (the right panel). (B) Summary data showing the CRC, R_max, and EC₅₀ of CPA-induced vasorelaxation in the presence of either L-NNA + INDO (n = 6) or L-NNA + INDO (&) + 10 μM SN-6 (n = 6). Data were expressed as percentage of NE (5 μM)-induced vasoconstriction and shown as means ± SEM. ^***p < 0.001 and ns, no significance.