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. 2021 Mar 9;12:611772. doi: 10.3389/fphys.2021.611772

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Copyright © 2021 Ouahmi, Courjon, Morand, François, Bruckert, Lombardi, Esnault, Seitz-Polski, Demonchy, Dellamonica and Boyer-Suavet.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significant proteinuria is associated with an increased risk to develop severe disease and longer hospitalization in patients with COVID-19 disease. Patients with higher proteinuria presented an increased risk to develop severe disease and to require admission to the intensive care unit. Kaplan-Meier analysis of the effect of proteinuria >0.3 g/g on length of stay in patients hospitalized with SARS-CoV-2 infection showed that patients with proteinuria greater than 0.3 g/g presented a longer hospitalization (log-rank p = 0.0002).