TABLE 4.

Correlation between p-JNK expression and patients’ chemotherapy side effects.

Parameters	Low p-JNK	High p-JNK	χ2	P value
Cases (n)	36	68
Decreased appetite			0.004	0.949
No	6 (16.67%)	11 (16.18%)
Yes	30 (83.33%)	57 (83.82%)
Nausea			0.017	0.897
No	4 (11.11%)	7 (10.29%)
Yes	32 (88.89%)	61 (89.71%)
Vomiting			0.487	0.485
No	19 (52.78%)	31 (45.59%)
Yes	17 (47.22%)	37 (54.41%)
Diarrhea			0.225	0.635
No	33 (91.67%)	64 (94.12%)
Yes	3 (8.33%)	4 (5.88%)
Mouth ulcers			3.851	0.049
No	34 (94.44%)	68 (100.00%)
Yes	2 (5.56%)	0 (0.00%)
Alopecia			0.446	0.504
No	15 (41.67%)	33 (48.53%)
Yes	21 (58.33%)	35 (51.47%)
Peripheral neurotoxicity			0.004	0.949
No	30 (83.33%)	57 (83.82%)
Yes	6 (16.67%)	11 (16.18%)
Anemia			2.781	0.095
Grade 0	15 (41.67%)	40 (58.82%)
Grade 1-2	21 (58.33%)	28 (41.18%)
Grade 3-4	0 (0.00%)	0 (0.00%)
Leukopenia			4.347	0.113
Grade 0	11 (30.56%)	13 (19.12%)
Grade 1-2	14 (38.89%)	41 (60.29%)
Grade 3-4	11 (30.56%)	14 (20.59%)
Neutropenia			0.979	0.613
Grade 0	7 (19.44%)	13 (19.12%)
Grade 1-2	12 (33.33%)	29 (42.65%)
Grade 3-4	17 (47.22%)	26 (38.24%)
Thrombocytopenia			0.099	0.752
Grade 0	28 (77.78%)	51 (75.00%)
Grade 1-2	8 (22.22%)	17 (25.00%)
Grade 3-4	0 (0.00%)	0 (0.00%)
Gastrointestinal reaction			1.910	0.385
Grade 0	4 (11.11%)	8 (11.76%)
Grade 1-2	31 (86.11%)	60 (88.24%)
Grade 3-4	1 (2.78%)	0 (0.00%)
Myelosuppression			0.152	0.927
Grade 0	5 (13.89%)	10 (14.71%)
Grade 1-2	10 (27.78%)	21 (30.88%)
Grade 3-4	21 (58.33%)	37 (54.41%)
Hepatic dysfunction			0.131	0.717
Grade 0	22 (61.11%)	44 (64.71%)
Grade 1-2	14 (38.89%)	24 (35.29%)
Grade 3-4	0 (0.00%)	0 (0.00%)