Table 1.
Effects of puerarin (PR) administration on plasma biochemical parameters and immune cell numbers in piglets infected with PEDV.
| Items | Control | PEDV | PEDV + PR |
|---|---|---|---|
| Plasma biochemical parameters | |||
| ALT (U/L) | 75.6 ± 4.35b | 63.5 ± 5.66a | 75.2 ± 8.84b |
| AST (U/L) | 43.3 ± 8.35a | 55.6 ± 8.77b | 46.3 ± 3.56a |
| AST/ALT | 0.63 ± 0.14a | 0.79 ± 0.16b | 0.67 ± 0.19ab |
| Total bilirubin (μmol/L) | 11.1 ± 4.22b | 6.62 ± 0.84a | 12.3 ± 6.86b |
| Total protein (g/L) | 54.2 ± 3.45 | 52.2 ± 1.98 | 51.7 ± 3.02 |
| Albumin (g/L) | 29.6 ± 2.22 | 28.0 ± 1.25 | 28.6 ± 2.58 |
| Cholesterol (mmol/L) | 2.22 ± 0.42a | 2.95 ± 0.23b | 2.42 ± 0.30a |
| Triglyceride (mg/dL) | 0.72 ± 0.14b | 0.50 ± 0.12a | 0.72 ± 0.21b |
| Urea nitrogen(mmol/L) | 4.11 ± 1.56b | 1.13 ± 0.15a | 3.41 ± 1.58b |
| ALP (U/L) | 356 ± 91.2a | 439 ± 78.6b | 345 ± 74.6a |
| Creatinine (µmol/L) | 73.8 ± 8.05 | 75.8 ± 9.27 | 77.5 ± 5.30 |
| Glucose (mmol/L) | 5.01 ± 0.57 | 5.28 ± 0.39 | 5.00 ± 0.85 |
| GGT (mmol/L) | 43.3 ± 8.27 | 41.4 ± 9.52 | 41.6 ± 12.8 |
| Blood cell counts | |||
| White blood cells (109/L) | 8.85 ± 2.04a | 12.9 ± 1.99b | 9.97 ± 3.40a |
| Neutrophils (109/L) | 3.45 ± 1.02a | 5.56 ± 0.18b | 3.45 ± 1.09a |
| Lymphocytes (109/L) | 4.86 ± 1.17a | 6.96 ± 1.10b | 5.91 ± 2.29ab |
| Monocytes (109/L) | 0.34 ± 0.08b | 0.21 ± 0.07a | 0.36 ± 0.16b |
| Monocyte ratio (%) | 3.37 ± 1.07b | 2.03 ± 0.71a | 3.09 ± 0.91b |
| Red blood cells (1012/L) | 5.95 ± 0.49a | 6.53 ± 0.42b | 6.11 ± 0.23a |
| MPV (fL) | 9.24 ± 0.72b | 8.09 ± 0.86a | 8.99 ± 0.49b |
| PDWR (%) | 68.6 ± 4.06b | 61.8 ± 4.91a | 67.6 ± 4.68b |
Values are mean and SD, n = 8.
a,bWithin a row, means with different superscripts differ (< 0.05).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, γ-glutamyltransferase; MPV, mean platelet volume; PDWR, Platelet distribution width ratio.