Table 3.

Univariate and multivariate analyses of risk factors for recurrence.

	Univariate analysis		Multivariate analysis
Age (≤ 65 years)	1.57 (0.77–3.39)	0.217
Sex (male)	0.90 (0.49–1.84)	0.768
Resectability status (R)	1.05 (0.48–2.62)	0.915
CA19-9 before initial treatment (≥ 100 U/mL)	2.27 (1.09–4.58)	0.029	1.99 (0.95–4.05)	0.067
Tumor position (ph)	1.74 (0.85–3.76)	0.131
Tumor size (≥ 20 mm)	1.92 (0.87–4.83)	0.110
Anterior serosal invasion (positive)	2.86 (1.19–8.47)	0.017	2.39 (0.98–7.14)	0.055
Retroperitoneal invasion (positive)	1.85 (0.77–5.47)	0.179
Portal vein invasion (positive)	1.62 (0.64–3.60)	0.284
Lymph node metastasis (positive)	1.54 (0.75–3.31)	0.241
Residual cancer (R1)	1.73 (0.51–4.46)	0.339
CITC, SAHH double positive	0.39 (0.18–0.79)	0.009	0.45 (0.21–0.93)	0.030