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. 2021 Mar 22;11:6581. doi: 10.1038/s41598-021-85820-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Histological evaluation. Prussian blue staining of brain of pigs after SPION pMSCs transplantation in contralateral [(A) ×5 magnification, (A′) ×40 magnification] and ipsilateral hemisphere [(B) ×5, (B′) ×40 magnification]. DAPI staining of brain of pigs after SPION pMSC transplantation in collateral [(C) ×40 magnification] and ipsilateral hemisphere [(D) ×40 magnification]. Red spots indicate iron oxide nanoparticles present in pMSCs.