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. 2021 Mar 22;11:6571. doi: 10.1038/s41598-021-86067-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CT-guided stereotactic prostate radiation therapy (CT-SPRT) technique. (a) Diagram depicting intra-prostatic contrast injection to enable CT-visualization of the prostate (b; Left panel) and CT-guided targeting for X-ray irradiation of the prostate (d; Right panel); (c) Diagram depicting administration of a single fraction 25 Gy CT-targeted unilateral anterior prostate lobe X-ray radiation (CT-SPRT). Contralateral non-irradiated lobe acting as an internal control.