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. 2021 Mar 22;11:6483. doi: 10.1038/s41598-021-85869-0

Table 2.

Laboratory findings of patients with COVID-19.

Laboratory findings Reference range Mild (n = 21) Moderate (n = 32) p
Blood cell count
White blood cell count, × 109/L 3.5–9.5 5.1[4.05–5.2] 5.2[3.82–6.25] 0.894a
Neutrophil count, × 109/L 1.8–6.3 2.11[1.69–3.23] 3.12[1.88–4.33] 0.068a
Neutrophil percentage, % 40–75 43.9[37.8–54.2] 57.3[48.25–64.7]  < 0.001a
Lymphocyte count, × 109/L 1.1–3.2 2.25[1.62–2.85] 1.65[1.21–2.10] 0.010a
Lymphocyte percentage, % 20–50 44.0[35.8–50.05] 33.5[28.7–41.3] 0.003a
NLR 0.96[0.72–1.47] 1.74[1.19–2.18]  < 0.001a
Haemoglobin, g/L 130–175 134[127.5–141.5] 142.0[123.5–148.5] 0.467a
Platelet count, × 109/L 125–350 210[191.5–247.0] 195.0[171.0–268] 0.743a
Blood biochemistry
Albumin, g/L 40–50 44.4[43.25–46.55] 43.15[41.52–44.97] 0.072a
ALT, U/L 9–50 14.2[10.5–20.45] 18.1[6.51–12.75] 0.029a
AST, U/L 15–40 18.6[15.5–20.85] 20.5[17.2–24.85] 0.256a
Total bilirubin, mmol/L 1.7–23 10.13[6.84–12.28] 8.88[6.56–12.75] 0.611a
Potassium, mmol/L 3.5–5.3 4.20[4.12–4.72] 4.47[4.13–4.95] 0.317a
Sodium, mmol/L 137–147 139.6[138.25–141.55] 139.45[137.92–141.45] 0.849a
Creatinine, μmol/L 57–97 59.2[54.15–66.45] 67.7[58.67–91.27] 0.033a
LDH, U/L 120–250 163.30[143.25–199.15] 181.05[149.85–212.00] 0.252a
cTnI, pg/mL 0–40 0.1[0.1–0.1] 0.1[0.1–0.1] 0.418a
CKMB, U/L 0–25 8.8[8.0–12.1] 10.3[8.125–14.475] 0.287a
Triglyceride, mmol/L 0.6–1.7 0.68[0.54–1.01] 0.88[0.776–1.02] 0.052a
HDL, mmol/L 1.04–1.56 2.19[1.73–2.83] 1.45[1.13–2.42] 0.008a
LDL, mmol/L 1.03–3.38 2.21[1.65–2.42] 2.19[1.73–2.83] 0.335a
Total cholesterol, mmol/L 3.1–5.2 3.94[3.45–4.42] 3.80[3.25–4.61] 0.920a
Glucose, mmol/L 3.9–6.1 4.93[4.57–5.10] 4.92[4.72–5.19] 0.518a
Lactic acid, mmol/L 0–2 2.1[1.8–2.3] 2.1[1.7–2.4] 0.802a
Coagulation
PT, s 9.1–12.1 13.6[13.35–14.15] 13.6[13.12–14.00] 0.964a
APTT, s 25.4–38.4 39.8[35.5–42.55] 39.15[37.00–45.22] 0.418a
Fibrinogen, mg/dL 2–4 2.62[2.495–3.015] 3.48[2.88–3.87]  < 0.001a
D-dimer, mg/L 0–231 220[220–300] 270[220–402.5] 0.127a
Infection-related
PCT, ng/mL 0.02–0.5 0.03[0.03–0.375] 0.04[0.03–0.067] 0.007a
CRP, mg/L 0–6 0.39[0.165–1.335] 3.41[0.865–17.24] 0.010a
ESR, mm/h 0–15 7.0[4.0–10.5] 14.0[7.25–24.5] 0.001a
Radiologic findings
GGO 28(87.5)
Consolidation 14(43.8)
Lesion distribution
 Local 17(53.1)
 Multifocal 15(46.9)
 Unilateral 22(68.8)
 Bilateral 10(31.3)
Total CT score 2[1–3]

Laboratory findings are presented as the median (25% quantile-75% quantile); radiologic findings are presented as the number of cases (percentage).

NLR neutrophil-to-lymphocyte ratio; ALT alanine aminotransferase; AST aspartate aminotransferase; LDH lactate dehydrogenase; cTnI cardiac troponin I; CKMB MB isoenzyme of creatine kinase; HDL high density lipoprotein; LDL low density lipoprotein; PT prothrombin time; APTT activated partial thromboplastin time; PCT procalcitonin; CRP C-reactive protein; ESR erythrocyte sedimentation rate; GGO ground glass opacity.

ap according to the Wilcoxon rank sum test.

All bold values indicate significant differences at the level of 0.05 for a highlight purpose.