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. 2021 Feb 19;44(4):874–882. doi: 10.2337/dc20-1639

Table 2.

Base-case analysis from the health care sector perspective for the 10-year simulation cost-effectiveness

UC EXER CBT EXER+CBT
Intervention-related cost ($) 1,615 1,346 1,757 1,736
Cost of the EXER or CBT intervention 0 320 694 1,033
Resource use and cost of medical care outside Program ACTIVE II 1,615 1,026 1,063 704
Outcome cost ($) 74,411 74,368 74,865 74,693
Total cost ($) 76,026 75,714 76,622 76,429
QALYs 4.665 5.047 4.955 5.355
Incremental total cost vs. UC ($) −313 596 403
Incremental QALY vs. UC 0.382 0.290 0.690
ICER vs. UC ($) Cost saving 2,058 585

Cost-effectiveness of the Program ACTIVE II interventions assuming the diminishing intervention effects after the end of the trial.

Intervention-related cost refers to the per-participant costs over the 15-month intervention period of Program ACTIVE II and includes the costs of the EXER intervention, CBT intervention, and EXER+CBT intervention and the resource use and cost of medical care outside Program ACTIVE II.

Outcome cost refers to the per-participant medical costs of type 2 diabetes and its complications.