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. 2021 Mar 22;11:6515. doi: 10.1038/s41598-021-85646-z

Table 5.

Differences in the clinical characteristics of the population according to median levels of admission hsTnT.

Variable N Admission hs Troponin P-Value
Below the median Above the median
Age, years 200 59 (13) 78 (11)  < 0.001
Male sex, n (%) 200 39 (38) 30 (31) 0.302
Current smoking, % 187 4 (4) 2 (2) 0.494
PaO2* 182 77 (63–87) 61 (50–74)  < 0.001
PaO2/FiO2* 194 300 (240–371) 257 (195–324) 0.001
Glucose, mg/dL 194 121 (34) 148 (72)  < 0.001
Haemoglobin, g/dl* 195 14 (12.7–14.9) 12.9 (11.4–14.6) 0.006
Leukocyte count, cells/μl* 197 6380(4780–8330) 6690(5240–10,060) 0.079
Lymphocyte count, cells/μl* 197 1100 (690–1330) 835 (540–1116)  < 0.001
Neutrophils count, cells/μl* 194 4500 (3120–6240) 5600 (3447–7665) 0.036
Platelets count, cells/μl* 197 196 (149–248) 175 (129–238) 0.126
INR* 193 1.21 (1.13–1.28) 1.25 (1.18–1.48) 0.002
Total Bilirubin, mg/dL* 194 0.44 (0.32–0.63) 0.56 (0.38–0.76) 0.038
Aspartate transaminase, U/L* 186 32 (24–50) 34 (25–51) 0.737
Alanine transaminase, U/L* 195 33 (23–49) 22 (14–36)  < 0.001
Creatinine, mg/dL* 195 0.89 (0.78–1.03) 1.24 (0.96–1.83)  < 0.001
Sodium, mEq/L* 196 138 (135–140) 138(134–141) 0.467
Potassium, mEq/L* 192 3.98 (3.73–4.25) 4.13 (3.84–4.47) 0.007
D-dimer, mg/L* 75 0.32 (0.21–0.69) 0.67 (0.35–1.10) 0.021
Lactate Dehydrogenase, U/L* 109 283 (216–405) 357 (251–467) 0.039
Creatine phosphokinase, U/L* 100 76 (50–213) 92 (56–207) 0.587
High sensitivity troponin T, ng/L* 200 9 (6–12) 41 (26–85)  < 0.001
Procalcitonin, ng/mL* 177 0.08 (0.05–0.16) 0.19 (0.10–0.65)  < 0.001
C-reactive protein, mg/dl* 193 4.31 (1.79–10.67) 8.88 (4.87–18.49)  < 0.001
Comorbidities
 Chronic obstructive pulmonary disease, n (%) 200 4 (4) 23 (24)  < 0.001
 Asthma, n (%) 199 8 (8) 4 (4) 0.286
 Diabetes mellitus, n (%) 200 9 (9) 29 (30)  < 0.001
 Arterial hypertension, n (%) 200 31 (30) 63 (65)  < 0.001
 History of cardiovascular disease, n (%) 200 18 (17) 49 (50)  < 0.001
 History of cerebrovascular disease, n (%) 200 3 (3) 18 (19)  < 0.001
 Diagnosis of dementia, n (%) 200 2 (2) 13 (13) 0.002
 Diagnosis of Cancer, n (%) 200 12 (12) 17 (17) 0.238
 Haematological malignancy, n (%) 200 0 (0) 4 (4) 0.037
 Chronic kidney disease, n (%) 200 2 (2) 14 (14) 0.001
 Dialysis, n (%) 200 0 (0) 3 (3) 0.072
 Chronic liver disease, n (%) 200 1 (1) 6 (6) 0.045

P-values are derived from independent samples Student’s T Test or the Mann Whitney test for continuous variables and the chi squared test for categorical variables; *Median and interquartile range.