Table 3.
Genes detected in the MAGMA gene analyses.
| Environment | Gene | Chr | BPSTART | BPSTOP | PGWEIS | PGWAS |
|---|---|---|---|---|---|---|
| Alcohol intake | CLDN4 | 7 | 73,213,872 | 73,247,014 | 1.16e−7 | 0.190 |
| WBSCR27 | 7 | 73,248,920 | 73,256,865 | 1.44e−6 | 0.093 | |
| Chronic pain | VPS9D1 | 16 | 89,773,542 | 89,787,394 | 5.59e−7 | 0.532 |
| FANCA | 16 | 89,803,957 | 89,883,065 | 1.30e−6 | 0.016 | |
| Intelligence | EIF5A | 12 | 7,210,318 | 7,215,774 | 8.43e−7 | 0.116 |
| POLE | 12 | 133,200,348 | 133,263,951 | 1.18e−6 | 0.080 | |
| Family satisf. | CWC27 | 5 | 64,064,757 | 64,314,590 | 1.22e−6 | 0.054 |
| Sexual assault | FHIT | 3 | 59,735,036 | 61,237,133 | 1.15e−6 | 1e−4 |
| Social activities | ZSWIM3 | 20 | 44,486,256 | 44,507,761 | 1.85e−6 | 0.097 |
| Y/o schooling | TUSC5 | 17 | 1,182,957 | 1,204,281 | 2.14e−6 | 0.702 |
Results from MAGMA gene analysis of 19,831 genes, using the GWEIS interaction p-values as input (p < 0.05/19,831 = 2.52e−6); No gene survived additional Bonferroni correction for the number of environments analysed (p < 2.52e−6/25 = 1.01e−7).