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. 2021 Mar 22;11:6518. doi: 10.1038/s41598-021-86032-5

Figure 3.

Figure 3

Identification of transcription factors that mediate secondary vitamin D responses. Log2 fold changes in gene expression versus time-matched control samples are displayed per time point for 47 genes coding for transcription factors, which have been predicted to be primary 1,25(OH)2D3 targets genes (a). Display of VDR ChIP-seq11 and FAIRE-seq15 data in the IGV browser illustrates binding of VDR in regions of open chromatin in the loci of the four transcription factors PPARG, CEBPB, NFIA and NR1I2 (b–e).