Fig. 3.

Dose-response curves summarizing the same data shown in Fig. 2 for MCAM and naloxone in reversing ventilatory-depressant effects of 0.178 mg/kg fentanyl intravenously. Each data point is the mean minute volume for 5 minutes after infusion of vehicle (V), MCAM, or naloxone and averaged (±1 S.E.M.) among eight rats. Ordinate: minute volume presented as a percent of baseline. Abscissa: dose of MCAM or naloxone in mg/kg body weight intravenously. C represents a control session in which rats received only vehicle.