TABLE 1.
Langendorff heart parameters during acetate infusion
| Heart parameter | HR | Pdev | dP/dtmax | dP/dtmin | RPP |
|---|---|---|---|---|---|
| bpm | mmHg | mmHg/s | mmHg/s | HR × Pdev | |
| Baseline | |||||
| Saline | 371 ± 68 | 82 ± 18 | 3463 ± 806 | −2548 ± 693 | 29688 ± 2418 |
| Acetate | 351 ± 20 | 85 ± 10 | 3272 ± 850 | −2111 ± 614 | 30023 ± 2132 |
| 30-min infusion | |||||
| Saline | 354 ± 40 | 86 ± 20 | 3892 ± 1030 | −2244 ± 501 | 30083 ± 2177 |
| Acetate | 275 ± 21* | 104 ± 33 | 4217 ± 1821 | −2087 ± 777 | 28147 ± 4377 |
Isolated ex vivo Langendorff heart hemodynamic data were recorded from the left ventricle at baseline, after 30 minutes of saline infusion, and after 30 minutes of acetate infusion (10 mM working concentration). n = 8 saline, n = 5 acetate. Values are means ± S.D.
*
P = 0.0068.