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. 2021 Mar;127:102033. doi: 10.1016/j.tube.2020.102033

Figure 2.

Figure 2

Volcano plots showing genes significantly differentially expressed between IGRA+ and IGRA- individuals. Plots are shown for TB1-stimulated samples at Visit (V) 1 [A] and V2 [B] and TB2-stimulated samples at V1 [C] and V2 [D]. Genes overexpressed in IGRA+s with log2Foldchange (LFC) > 1 and Benjamini-Hochberg adjusted p value ≤ 0.05 are shown in red. Genes underexpressed in IGRA+ individuals with LFC <-1 and BH adjusted p value ≤ 0.05 are shown in blue. Genes with LFC >2.7 and < −1.7 are annotated with their gene symbols. Dotted line denotes the significance cut-off (BH adjusted p value ≤ 0.05).