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. 2021 Mar 23;784:145596. doi: 10.1016/j.gene.2021.145596

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Fig. 1 — SARS-CoV-2-related viruses in Malayan pangolins (Manis javanica). A) Phylogeny of SARS-CoV-2 and related viruses sampled in bats and pangolins. SARS-CoV-2 from the COVID-19 epidemic are coloured in red, while related SARS-like coronaviruses are coloured in blue. The sample P1E (EPI_ISL_410539) is highlighted by a green box. Tree obtained from the Nextstrain website. B) and C) Identity plot for the alignment of ORF8 (B) and spike (C) genes from SARS-CoV-2-related viruses sequenced from five pangolin samples collected in Guangxi, China. Highlighted in B) is the ORF8 gene region with the mutation C27960T causing the premature stop codon Q23stop observed in sample P1E. The alignments include the reference SARS-CoV-2 genome (NC_045512.2). The most conserved positions are indicated by green bars.