Fig. 4.

Effects of Aroclor1260, CAR and PXR on bacterial abundance at the genus level. The relative abundances of identified bacteria at the genus level, namely (A) Blautia, (B) Dorea, (C) Roseburia, (D) Ruminococcus, (E) Butyricimonas, (F) Lactobacillus, (G) Bifidobacterium and (H) Akkermansia were plotted for the different groups. Values are mean ± SEM, p < 0.05, a- Δ due to Aroclor1260 exposure within genotype, b, b*- Δ between WT and Car^−/− without or with Aroclor1260 exposure, c, c*- Δ between WT and Pxr^−/− without or with Aroclor1260 exposure, d, d*- Δ between Car and Pxr ablation without or with Aroclor1260 exposure.