Fig. 5.

Effects of Aroclor1260, CAR and PXR on bacterial abundance at the species level. A heatmap depicting the relative abundances of identified bacteria at the species level, namely B. Adolescentis, B. Pseudolongum, R. Gnavus, R. Callidus, F. Prausnitzii, C. Aerofaciens, A. Muciniphila and G. Formicilis for the different groups. Values are presented as -log (mean relative abundance), thereby lower values are reflective of higher relative abundance and vice versa. p < 0.05, a- Δ due to Aroclor1260 exposure within genotype, b, b*- Δ between WT and Car^-/- without or with Aroclor1260 exposure, c, c*- Δ between WT and Pxr^-/- without or with Aroclor1260 exposure, d, d*- Δ between Car and Pxr ablation without or with Aroclor1260 exposure.