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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Q J Nucl Med Mol Imaging. 2020 Feb 18;64(1):4–20. doi: 10.23736/S1824-4785.20.03230-6

Figure 2. Comparison between 68Ga-DOTATATE and 18F-FDG coronary PET inflammation imaging.

Figure 2.

Images from a 57-year old man with acute coronary syndrome who presented with deep anterolateral T-wave inversion (arrow) on electrocardiogram (A) and serum troponin-I concentration elevated at 4,650 ng/l (NR: <17 ng/l). Culprit left anterior descending artery stenosis (dashed oval) was identified by X-ray angiography (B). After the patient underwent percutaneous coronary stenting (C), residual coronary plaque (*inset) with high-risk morphology (low attenuation and spotty calcification) is evident on CT angiography (D, E). Use of 68Ga-DOTATATE PET (F, H, I) clearly detected intense inflammation in this high-risk atherosclerotic plaque/distal portion of the stented culprit lesion (arrow) and recently infarcted myocardium (*). In contrast, using 18F-FDG PET (G, J), myocardial spillover completely obscures the coronary arteries. CT = computed tomography; 18F-FDG = fluorine-18-labeled fluorodeoxyglucose; 68Ga-DOTATATE = gallium-68-labeled DOTATATE; PET = positron emission tomography. Adapted with permission from reference 13