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. 2020 Dec 25;73(3):511–529. doi: 10.1002/iub.2434

FIGURE 2.

FIGURE 2

(a) The consequences of nucleo‐mitochondrial mismatch on basal ROS production in culture cells 59 and animal models. 67 (b) Mitohormesis contributes to healthy ageing. An increase in non‐pathological basal mtROS levels induce regular mild mitochondrial stress, priming the mitochondrial adaptive response to elevated levels of cellular stress. BL/6NZB conplastic mice present a delay in the hallmarks of aging detailed in the schematic